352423-64-4

Upstream product

• 352423-63-3 4-bromo-3-[2-(2,5-dihydro-4-methyl-5-oxo-2-furanyl)-2-[methyl(phenylmethyl)amino]ethyl]-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester 
• 52488-36-5 4-bromo-1H-indole 
• 151726-06-6 4-bromo-3-(2-oxoethyl)-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester 
• 151726-05-5 4-bromo-3-cyanomethyl-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester 
• 64258-88-4 1-(4-bromo-1H-indol-3-yl)-N,N-dimethylmethanamine 
• 89245-35-2 2-(4-bromo-1H-indol-3-yl)acetonitrile 

Relevant academic research and scientific papers

Applications of vinylogous Mannich reactions. Total syntheses of the Ergot alkaloids rugulovasines A and B and setoclavine

Concise syntheses of the Ergot alkaloids rugulovasine A (3a), rugulovasine B (3b), and setoclavine (2) have been completed by strategies that feature inter- and intramolecular vinylogous Mannich reactions as the key steps. Thus, the first synthesis of 3a,