35245-26-2

Basic information

• Product Name: NAPHTHOL AS-D CHLOROACETATE
• Synonyms: LEDER STAIN;3-HYDROXY-2-NAPHTHOIC-O-TOLUIDIDE CHLOROACETATE;NAPHTHOL AS-D CHLOROACETATE;3-[[(2-methylphenyl)amino]carbonyl]-2-naphthyl chloroacetate;NAPHTHOL AS-D-CHLOROACETATE, FOR HISTOLO GY;NAPHTHOL AS-D CHLOROACETATE CRYSTALLINE;3-[(2-Methylphenyl)carbamoyl]-2-naphthalenyl=chloroacetate;Chloroacetic acid 3-(2-methylphenylcarbamoyl)-2-naphtyl ester
• CAS NO: 35245-26-2
• Molecular Formula: C20H16ClNO3
• Molecular Weight: 353.8
• EINECS: 252-463-5
• Product Categories: Cytochemistry Products;Hematology and Histology;substrate
• Mol File: 35245-26-2.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 460.3 °C at 760 mmHg
• Flash Point: 232.2 °C
• Appearance: WHITE TO OFF-WHITE POWDER
• Density: 1.321 g/cm³
• Vapor Pressure: 1.18E-08mmHg at 25°C
• Refractive Index: 1.667
• Storage Temp.: 2-8°C
• PKA: 12.33±0.70(Predicted)
• CAS DataBase Reference: NAPHTHOL AS-D CHLOROACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: NAPHTHOL AS-D CHLOROACETATE(35245-26-2)
• EPA Substance Registry System: NAPHTHOL AS-D CHLOROACETATE(35245-26-2)

Safety Data

• Hazard Codes: F,C,T
• Statements: 19-34-11-35-20/21/22-61-46-45
• Safety Statements: 22-24/25-45-36/37/39-26-16-53
• WGK Germany: 3
• F: 8-10-21
• Hazardous Substances Data: 35245-26-2(Hazardous Substances Data)

Usage

Description

Naphthol AS-D chloroacetate is a chemical compound that serves as a substrate for specific enzyme assays. It is particularly used in the detection and measurement of naphthol-AS-D-chloroacetate-esterase (CIAE) activity, which is an important enzyme in various biological processes.

Uses

Used in Diagnostic Applications:
Naphthol AS-D chloroacetate is used as a substrate for CIAE staining in diagnostic applications. This staining process helps in the identification and quantification of CIAE enzyme activity, which can be indicative of certain conditions or diseases.
Used in Research and Development:
In the field of research and development, Naphthol AS-D chloroacetate is utilized as a substrate to study the activity and properties of CIAE enzyme. This helps researchers understand the enzyme's role in biological processes and develop potential therapeutic strategies targeting this enzyme.
Used in Pharmaceutical Industry:
Naphthol AS-D chloroacetate is also used in the pharmaceutical industry for the development of drugs that target CIAE enzyme. By understanding the enzyme's function and its interaction with this substrate, researchers can design drugs that modulate CIAE activity, potentially leading to treatments for related conditions.
Used in Quality Control:
In the context of quality control, Naphthol AS-D chloroacetate is employed to ensure the accuracy and reliability of diagnostic tests and reagents. By using this substrate in test systems, manufacturers can verify the performance of their products and ensure they meet the required standards for CIAE enzyme detection and measurement.

InChI:InChI=1/C20H16ClNO3/c1-13-6-2-5-9-17(13)22-20(24)16-10-14-7-3-4-8-15(14)11-18(16)25-19(23)12-21/h2-11H,12H2,1H3,(H,22,24)