352463-54-8

Basic information

• Product Name: Acetaldehyde, 2-[(2-hydroxyethyl)amino]-, O-(phenylmethyl)oxime
• CAS NO: 352463-54-8
• Molecular Formula: C11H16N2O2
• Molecular Weight: 208.26
• Mol File: 352463-54-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Acetaldehyde, 2-[(2-hydroxyethyl)amino]-, O-(phenylmethyl)oxime(CAS DataBase Reference)
• NIST Chemistry Reference: Acetaldehyde, 2-[(2-hydroxyethyl)amino]-, O-(phenylmethyl)oxime(352463-54-8)
• EPA Substance Registry System: Acetaldehyde, 2-[(2-hydroxyethyl)amino]-, O-(phenylmethyl)oxime(352463-54-8)

Safety Data

• Hazardous Substances Data: 352463-54-8(Hazardous Substances Data)

Upstream product

• 141-43-5 ethanolamine 
• 101389-21-3 α-chloroacetaldoxime benzyl ether 

Downstream Products

• 294675-53-9 N-(2-hydroxyethyl)-N-[2-[(phenylmethoxy)imino]ethyl]-2-propenamide 
• 352463-56-0 4-[(2-(N-(2-(benzyloxyimino)ethyl)-N-(2-propenoyl)amino)ethoxy)carbonyl]butanoic acid 

Relevant articles and documents

Samarium diiodide-induced radical cyclization of oxime ether connected with formyl group: Synthesis of 4-pyrimidinyl- and 4-purinylpyrrolidin-3-ol nucleoside analogues

SmI2-induced 5-exo-trig radical cyclization of oxime ether intramolecularly connected with the formyl group was found to be particularly effective for preparing cyclic trans-amino alcohol in good chemical yield with a high degree of stereoselectivity. Its successful application to the synthesis of a novel class of 4-pyrimidinyl- and 4-purinylpyrrolidin-3-ol nucleoside analogues is also described.

Solid-phase tandem radical addition-cyclisation reaction of oxime ethers

The solid-phase tandem C-C bond-forming reactions of oxime ethers connected with α,β-unsaturated carbonyl groups proceeded effectively under iodine atom-transfer reaction conditions to give the azacycles or chiral oxacycles after cleavage of the resin.