35247-34-8Relevant academic research and scientific papers
CuII-Catalyzed Coupling with Two Ynone Units by Selective Triple and Sigma C-C and C-H Bond Cleavages
Nan, Jiang,Zhang, Jiawen,Hu, Yan,Wang, Chao,Wang, Tingting,Wang, Weitao,Ma, Yangmin,Szostak, Michal
, p. 1928 - 1933 (2021)
We report a new copper-catalyzed [2 + 2 + 1] annulation process through the selective cleavage of sigma and triple C-C and C-H bonds using two ynone units. This new methodology involves breaking multiple chemical bonds in a single operation, including CC, C-C, C-H, and N-O. These high-value adducts lead to a diverse collection of synthetically challenging trisubstituted indolizines by the simultaneous engagement of different bond-breaking events and show excellent fluorescence in green aqueous solutions.
