352524-61-9Relevant academic research and scientific papers
The synthesis and biological evaluation of a novel series of antimicrobials of the oxazolidinone class.
Sciotti, Richard J,Pliushchev, Marina,Wiedeman, Paul E,Balli, Darlene,Flamm, Robert,Nilius, Angela M,Marsh, Kennan,Stolarik, DeAnne,Jolly, Robert,Ulrich, Roger,Djuric, Stevan W
, p. 2121 - 2123 (2002)
A novel series of antimicrobials of the oxazolidinone class is disclosed. These compounds are characterized relative to previously described analogues by a 'halostilbene-derived' pharmacophore and demonstrate enhanced antimicrobial activity against key Gram-positive pathogens when compared to Linezolid.
OXAZOLIDINONE CHEMOTHERAPEUTIC AGENTS
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, (2008/06/13)
Compounds of the formula or therapeutically acceptable salts or prodrugs thereof, are useful for treating bacterial infections, psoriasis, arthritis, and toxicity due to chemotherapy. Preparation of the compounds, compositions containing the compounds, an
Oxazolidinone chemotherapeutic agents
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, (2008/06/13)
Compounds of formula (I) or therapeutically acceptable salts or prodrugs thereof, are useful for treating bacterial infections, psoriasis, arthritis, and toxicity due to chemotherapy. Preparation of the compounds, compositions containing the compounds, an
Synthesis of N-arylated oxazolidinones via a palladium catalyzed cross coupling reaction. Application to the synthesis of the antibacterial agent Dup-721
Madar, David J.,Kopecka, Hana,Pireh, Daisy,Pease, Jonathan,Pliushchev, Marina,Sciotti, Richard J.,Wiedeman, Paul E.,Djuric, Stevan W.
, p. 3681 - 3684 (2007/10/03)
A method for the intermolecular coupling of aryl bromides and oxazolidinones is described. Application to intermediates useful for the preparation of a known class of antibacterial agent and the synthesis of the known antibacterial oxazolidinone Dup-721 are described.
Oxazolidinone chemotherapeutic agents
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, (2008/06/13)
Compounds of formula (I) or therapeutically acceptable salts or prodrugs thereof, are useful for treating bacterial infections, psoriasis, arthritis, and toxicity due to chemotherapy. Preparation of the compounds, compositions containing the compounds, an
