352535-81-0 Usage
Uses
Used in Organic Chemistry:
4-Bromo-2,6-difluorophenylboronic acid is used as a reagent for various organic reactions, particularly in the Suzuki coupling process. This reaction is essential for the synthesis of complex organic molecules, where the boronic acid plays a crucial role in facilitating the cross-coupling.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-Bromo-2,6-difluorophenylboronic acid is used as a building block for the synthesis of various pharmaceutical compounds. Its unique structure and reactivity make it a valuable component in the development of new drugs and medicinal agents.
Used in Material Science:
4-Bromo-2,6-difluorophenylboronic acid is employed as a precursor in the synthesis of advanced materials, such as polymers and composites, where its boron and halogen atoms can impart specific properties to the final product, like improved thermal stability or enhanced electrical conductivity.
Used in Research and Development:
In academic and industrial research settings, 4-Bromo-2,6-difluorophenylboronic acid is used as a key intermediate in the exploration of new chemical reactions and pathways. Its versatility in participating in various coupling reactions makes it an essential tool for chemists working on innovative synthetic strategies and methodologies.
Check Digit Verification of cas no
The CAS Registry Mumber 352535-81-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,2,5,3 and 5 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 352535-81:
(8*3)+(7*5)+(6*2)+(5*5)+(4*3)+(3*5)+(2*8)+(1*1)=140
140 % 10 = 0
So 352535-81-0 is a valid CAS Registry Number.
InChI:InChI=1/C6H4BBrF2O2/c8-3-1-4(9)6(7(11)12)5(10)2-3/h1-2,11-12H
352535-81-0Relevant articles and documents
Modular Generation of (Iodinated) Polyarenes Using Triethylgermane as Orthogonal Masking Group
Deckers, Kristina,Fricke, Christoph,Hupperich, Daniel,Kreisel, Tatjana,Mendel, Marvin,Queen, Adele E.,Riegger, Julian,Schoenebeck, Franziska
supporting information, (2022/03/31)
While the modular construction of molecules from suitable building blocks is a powerful means to more rapidly generate a diversity of molecules than through customized syntheses, the further evolution of the underlying coupling methodology is key to realize widespread applications. We herein disclose a complementary modular coupling approach to the widely employed Suzuki coupling strategy of boron containing precursors, which relies on organogermane containing building blocks as key orthogonal functionality and an electrophilic (rather than nucleophilic) unmasking event paired with air-stable PdI dimer based bond construction. This allows to significantly shorten the reaction times for the iterative coupling steps and/or to close gaps in the accessible compound space, enabling straightforward access also to iodinated compounds.
A 2, 6 - difluoro - 4 - bromophenol preparation method (by machine translation)
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Paragraph 0016; 0024; 0025; 0026; 0027; 0031; 0032-0034, (2017/06/28)
The invention relates to a 2, 6 - difluoro - 4 - bromophenol preparation method, the preparation method in order to 3, 5 - difluoro bromobenzene as raw materials, after metalation reaction and oxidation reaction, prepare the high purity of the 2, 6 - difluoro - 4 - bromophenol, the preparation of the synthesizing method of the more inexpensive raw materials, low cost, easy operation, and is suitable for large-scale and continuous production, has very high application prospect. (by machine translation)
