352663-15-1

Basic information

• Product Name: 2'-amino-3'-cyano-7',7'-dimethyl-1-(hydroxymethyl)-1,3,5',6',7',8'-hexahydro-2,5'-dioxospiro[2H-indole-3,4'-(4'H)-chromene]
• Synonyms: 2'-amino-3'-cyano-7',7'-dimethyl-1-(hydroxymethyl)-1,3,5',6',7',8'-hexahydro-2,5'-dioxospiro[2H-indole-3,4'-(4'H)-chromene]
• CAS NO: 352663-15-1
• Molecular Formula: C20H19N3O4
• Molecular Weight: 365.38256
• Mol File: 352663-15-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2'-amino-3'-cyano-7',7'-dimethyl-1-(hydroxymethyl)-1,3,5',6',7',8'-hexahydro-2,5'-dioxospiro[2H-indole-3,4'-(4'H)-chromene](CAS DataBase Reference)
• NIST Chemistry Reference: 2'-amino-3'-cyano-7',7'-dimethyl-1-(hydroxymethyl)-1,3,5',6',7',8'-hexahydro-2,5'-dioxospiro[2H-indole-3,4'-(4'H)-chromene](352663-15-1)
• EPA Substance Registry System: 2'-amino-3'-cyano-7',7'-dimethyl-1-(hydroxymethyl)-1,3,5',6',7',8'-hexahydro-2,5'-dioxospiro[2H-indole-3,4'-(4'H)-chromene](352663-15-1)

Safety Data

• Hazardous Substances Data: 352663-15-1(Hazardous Substances Data)

Upstream product

• 50899-59-7 N-Hydroxymethylisatin 
• 126-81-8 dimedone 
• 109-77-3 malononitrile 

Relevant articles and documents

Versatile three-component synthesis of 2'-amino-1,2-dihydrospiro[(3H)- indole-3,4'-(4'H)-pyran]-2-ones

A versatile method for the synthesis of 2'-amino-1,2-dihydrospiro[(3H)- indole-3,4'-(4'H)-pyran]-2-ones has been suggested consisting in the three-component reaction of isatins, cyanoacetic acid derivatives, and α-methylenecarbonyl compounds (β-dicarbonyl compounds, activated phenols, and OH-substituted heterocycles) in ethanol in the presence of triethylamine as a catalyst. The reaction proceeds selectively to form spiro[(3H)-indole-3,4'-(4'H)-pyrans].