352695-01-3Relevant academic research and scientific papers
Halichondrin B: Synthesis of the C1-C22 subunit
Lambert, William T.,Hanson, Gregory H.,Benayoud, Farid,Burke, Steven D.
, p. 9382 - 9398 (2005)
Two efficient routes to the C1-C22 subunit of halichondrin B are described. The cage ketal 7, which contains 11 asymmetric centers embedded within the ABCDEF-ring framework, was assembled from (+)-conduritol E (27) in 18 steps and 4% overall yield. In a s
The lack of C2 molecular symmetry in (1R,2R,3S,6S)-3,6-dibenzyloxycyclohex-4-ene-1,2-diol.
Clark,Guzei,Ivanov,Burke,Lambert
, p. 844 - 845 (2001)
The results of a single-crystal X-ray experiment and density functional theory calculations performed for the title compound, C20H22O4, demonstrate that the lowest energy conformation of this molecule does not contain C2 molecular symmetry.
