35271-85-3Relevant academic research and scientific papers
The total synthesis of fukiic acid, an HIV-1 integrase inhibitor
Queffelec, Clemence,Bailly, Fabrice,Mbemba, Gladys,Mouscadet, Jean-Francois,Debyser, Zeger,Witvrouw, Myriam,Cotelle, Philippe
, p. 2268 - 2271 (2008/12/23)
A successful synthesis of fukiic acid is described in 7% overall yield (6 steps from veratraldehyde). rac-Fukiic acid was found to be a potent inhibitor of HIV-1 integrase but did not reveal any antiviral activity in the MT-4 cells assay.
