35272-09-4Relevant academic research and scientific papers
Cytotoxic substituted indolizines as new colchicine site tubulin polymerisation inhibitors
Sardaru, Monica-Cornelia,Craciun, Anda Mihaela,Al Matarneh, Cristina-Maria,Sandu, Isabela Andreea,Amarandi, Roxana Maria,Popovici, Lacramioara,Ciobanu, Catalina Ionica,Peptanariu, Dragos,Pinteala, Mariana,Mangalagiu, Ionel I.,Danac, Ramona
, p. 1581 - 1595 (2020)
A potential microtubule destabilising series of new indolizine derivatives was synthesised and tested for their anticancer activity against a panel of 60 human cancer cell lines. Compounds 11a, 11b, 15a, and 15j showed a broad spectrum of growth inhibitor
