3530-53-8Relevant articles and documents
A facile synthesis of D-ribo-C20-phytosphingosine and its C2 epimer from D-ribose
Martinkova, Miroslava,Gonda, Jozef,Pomikalova, Kvetoslava,Kozisek, Jozef,Kuchar, Juraj
, p. 1728 - 1738 (2011)
A facile synthetic route to D-ribo-C20-phytosphingosine 31 and its C2 epimer 32 is described. The Overman rearrangement of allylic trichloroacetimidates derived from the known ribose derivative 7 has been used as the key step. The subsequent functional group interconversions in rearranged products 14 and 15 followed by Wittig olefination, Pd/C-mediated reduction and the removal of protecting groups successfully constructed the final molecules.