353258-10-3Relevant academic research and scientific papers
Synthesis of Chiral Sulfoxides via Pd(II)-Catalyzed Enantioselective C-H Alkynylation/Kinetic Resolution of 2-(Arylsulfinyl)pyridines
Zhou, Tao,Jiang, Meng-Xue,Qian, Pu-Fan,Yao, Qi-Jun,Xu, Xue-Tao,Zhang, Kun,Shi, Bing-Feng
supporting information, p. 7910 - 7915 (2021/10/20)
A Pd(II)-catalyzed enantioselective C-H alkynylation of 2-(arylsulfinyl)pyridines via kinetic resolution using cheap and commercially available l-pGlu-OH as a chiral ligand is reported. A wide range of 2-(arylsulfinyl)pyridines were compatible with this p
Synthesis of Pyridylsulfonium Salts and Their Application in the Formation of Functionalized Bipyridines
Duong, Vincent K.,Horan, Alexandra M.,McGarrigle, Eoghan M.
supporting information, p. 8451 - 8457 (2020/11/12)
An S-selective arylation of pyridylsulfides with good functional group tolerance was developed. To demonstrate synthetic utility, the resulting pyridylsulfonium salts were used in a scalable transition-metal-free coupling protocol, yielding functionalized bipyridines with extensive functional group tolerance. This modular methodology permits selective introduction of functional groups from commercially available pyridyl halides, furnishing symmetrical and unsymmetrical 2,2′- A nd 2,3′-bipyridines. Iterative application of the methodology enabled the synthesis of a functionalized terpyridine with three different pyridine components.
