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1-(2-hydroxyethyl)-5-phenylpyrimidine-2,4,6(1H,3H,5H)-trione, commonly known as gabapentin, is a pharmaceutical compound that serves as a medication for treating epilepsy, neuropathic pain, and restless legs syndrome. It is characterized by its unique chemical structure, which includes a pyrimidine ring, a phenyl group, and a hydroxyethyl group that allows it to cross the blood-brain barrier and target the central nervous system. Gabapentin functions by binding to specific receptors in the brain, thereby inhibiting the release of neurotransmitters involved in pain signal transmission. However, it can also cause side effects such as dizziness, drowsiness, and weight gain, and may lead to tolerance and dependence with long-term use.

35359-14-9

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35359-14-9 Usage

Uses

Used in Pharmaceutical Industry:
1-(2-hydroxyethyl)-5-phenylpyrimidine-2,4,6(1H,3H,5H)-trione is used as an anticonvulsant for the treatment of epilepsy, providing relief from seizures and reducing their frequency. It is effective due to its ability to modulate the activity of certain receptors in the brain, which are involved in the generation and propagation of seizure activity.
1-(2-hydroxyethyl)-5-phenylpyrimidine-2,4,6(1H,3H,5H)-trione is used as an analgesic for the management of neuropathic pain, which is a type of pain caused by damage or disease affecting the somatosensory system. Its mechanism of action involves the inhibition of neurotransmitter release, thereby reducing the transmission of pain signals in the central nervous system.
1-(2-hydroxyethyl)-5-phenylpyrimidine-2,4,6(1H,3H,5H)-trione is used as a therapeutic agent for restless legs syndrome, a neurological disorder characterized by an uncontrollable urge to move the legs, often accompanied by uncomfortable sensations. Gabapentin helps alleviate these symptoms by targeting specific receptors in the brain that are involved in the regulation of motor function and sensory perception.
Additionally, gabapentin is used off-label for the treatment of anxiety, bipolar disorder, and alcohol withdrawal symptoms, due to its ability to modulate neurotransmitter release and influence the central nervous system. However, it is important to note that these uses are not officially approved and should be considered with caution, under the guidance of a healthcare professional.

Check Digit Verification of cas no

The CAS Registry Mumber 35359-14-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,3,5 and 9 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 35359-14:
(7*3)+(6*5)+(5*3)+(4*5)+(3*9)+(2*1)+(1*4)=119
119 % 10 = 9
So 35359-14-9 is a valid CAS Registry Number.

35359-14-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2-hydroxyethyl)-5-phenyl-1,3-diazinane-2,4,6-trione

1.2 Other means of identification

Product number -
Other names 1-(2-hydroxy-ethyl)-5-phenyl-pyrimidine-2,4,6-trione

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
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More Details:35359-14-9 SDS

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