35364-74-0Relevant academic research and scientific papers
Synthesis ofN-CF3hydrazines through radical trifluoromethylation of azodicarboxylates
Cao, Tingting,Crousse, Beno?t,Milcent, Thierry,Retailleau, Pascal
, p. 10351 - 10354 (2021/10/12)
We report here the synthesis of a novel family ofN-CF3hydrazines from a direct way involving the available and cheap Langlois reagent (CF3SO2Na). These derivatives have shown very high stability whatever the conditions used and are excellent precursors for building previously inaccessibleN-CF3functionalized compounds, such as substituted hydrazides, hydrazine-amino-acids, hydrazones,N-aziridines and pyrazoles.
