35364-86-4

Basic information

• Product Name: Benzene, 1-chloro-2-(diethoxymethyl)-
• Synonyms: o-chlorobenzaldehyde diethylacetal;2-chlorobenzaldehyde diethylacetal;o-Cl-Benzaldehyd-diaethylacetal;o-chlorobenzaldehyde diethyl acetal
• CAS NO: 35364-86-4
• Molecular Formula: C11H15ClO2
• Molecular Weight: 214.692
• Mol File: 35364-86-4.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 123-124 °C(Press: 15 Torr)
• Density: 1.088±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzene, 1-chloro-2-(diethoxymethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-chloro-2-(diethoxymethyl)-(35364-86-4)
• EPA Substance Registry System: Benzene, 1-chloro-2-(diethoxymethyl)-(35364-86-4)

Safety Data

• Hazardous Substances Data: 35364-86-4(Hazardous Substances Data)

Usage

General Description

Benzene, 1-chloro-2-(diethoxymethyl)- is a chemical compound with the formula C10H11ClO2. It is often used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. Benzene, 1-chloro-2-(diethoxymethyl)- is also used as a solvent in various industries. It is important to handle and use this chemical with caution as it is toxic and can cause irritation to the skin, eyes, and respiratory system. Additionally, prolonged exposure to this chemical can lead to serious health complications such as organ damage and cancer. Therefore, proper safety measures should be taken when working with or around benzene, 1-chloro-2-(diethoxymethyl)-.

Upstream product

• 89-98-5 2-chloro-benzaldehyde 
• 122-51-0 orthoformic acid triethyl ester 
• 64-17-5 ethanol 

Downstream Products

• 1203-68-5 2-Phenylbenzaldehyde 
• 945491-91-8 N-2-chlorobenzylidene-O,O-diethylthiophosphoramide 
• 945491-98-5 N-2-chlorobenzylidene-diphenylthiophosphinamide 
• 40138-16-7 2-formylbenzene boronic acid 
• 38018-63-2 3-(2-chlorophenyl)-1-(4-methylphenyl)-2-propen-1-one 
• 22966-11-6 (2E)-3-(2-chlorophenyl)-1-phenylprop-2-en-1-one 
• 69849-09-8 2-(2-chlorophenyl)-1,3-dithiane 

Relevant articles and documents

Practical acetalization and transacetalization of carbonyl compounds catalyzed by recyclable PVP-I

A novel PVP-I catalyzed acetalizations/transacetalizations of carbonyl compounds has been developed processing with a mild and easy handling fashion. Different types of Acyclic and cyclic acetals were prepared from carbonyl compounds or their acetals successfully. Further applications of newly developed catalytic combination were testified. This protocol featured with simplicity of operation, mild reaction condition, short reaction time, recyclable of catalyst and broad substrates scope with excellent yields.

Bis(perfluorooctanesulfonyl)imide supported on fluorous silica gel: Application to protection of carbonyls

The immobilization of bis(perfluorooctanesulfonyl)imide (HNPf2) on fluorous silica gel (FSG) and its utilization in protection of carbonyls have been investigated. This system is reasonably general and can be applied to converting several carbonyls to the corresponding acetals and ketals in good to excellent yields. There is no need for the use of anhydrous solvents or inert atmosphere. Recycling studies have shown that the FSG-supported HNPf2 catalyst can be readily recovered and reused several times without significant loss of activity.

2,4,4,6-Tetrabromo-2,5-cyclohexadienone (TABCO) as a versatile, efficient, and chemoselective catalyst for the acetalization and transacetalization of carbonyl compounds, the preparation of acetonides from epoxides and acylals (1,1-diacetates) from aldehydes

The efficient and chemoselective preparation of acetals and ketals from carbonyl compounds, transacetalization reactions, the conversion of epoxides to acetonides, and the preparation of acylals from aldehydes in the presence of catalytic amounts of 2,4,4,6-tetrabromo-2,5-cyclohexadienone (TABCO) are described.