Welcome to LookChem.com Sign In|Join Free

CAS

  • or

35370-80-0

Post Buying Request

35370-80-0 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

35370-80-0 Usage

General Description

2-Phenoxythioacetamide is a chemical compound that belongs to the class of thioamides. It is commonly used as a reagent in the synthesis of pharmaceuticals and agrochemicals. 2-PHENOXYTHIOACETAMIDE has demonstrated potential as an inhibitor of DNA-altering enzymes and has shown promise in the development of anti-cancer drugs. It also has applications in the field of organic synthesis, particularly in the preparation of heterocyclic compounds. Additionally, 2-Phenoxythioacetamide has been studied for its potential in controlling the growth of marine biofouling organisms. Overall, this chemical compound has shown versatility and potential in various fields of research and development.

Check Digit Verification of cas no

The CAS Registry Mumber 35370-80-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,3,7 and 0 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 35370-80:
(7*3)+(6*5)+(5*3)+(4*7)+(3*0)+(2*8)+(1*0)=110
110 % 10 = 0
So 35370-80-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H9NOS/c9-8(11)6-10-7-4-2-1-3-5-7/h1-5H,6H2,(H2,9,11)

35370-80-0 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • Alfa Aesar

  • (H26478)  2-Phenoxythioacetamide, 97%   

  • 35370-80-0

  • 250mg

  • 427.0CNY

  • Detail
  • Alfa Aesar

  • (H26478)  2-Phenoxythioacetamide, 97%   

  • 35370-80-0

  • 1g

  • 1178.0CNY

  • Detail

35370-80-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-phenoxyethanethioamide

1.2 Other means of identification

Product number -
Other names 1-amino-2-phenoxyethane-1-thione

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:35370-80-0 SDS

35370-80-0Relevant articles and documents

Dihydrothiazolopyridone derivatives as a novel family of positive allosteric modulators of the metabotropic glutamate 5 (mGlu5) receptor

Bartolomé-Nebreda, José Manuel,Conde-Ceide, Susana,Delgado, Francisca,Iturrino, Laura,Pastor, Joaquín,Pena, Miguel ángel,Trabanco, Andrés A.,Tresadern, Gary,Wassvik, Carola M.,Stauffer, Shaun R.,Jadhav, Satyawan,Gogi, Kiran,Vinson, Paige N.,Noetzel, Meredith J.,Days, Emily,Weaver, C. David,Lindsley, Craig W.,Niswender, Colleen M.,Jones, Carrie K.,Conn, P. Jeffrey,Rombouts, Frederik,Lavreysen, Hilde,Macdonald, Gregor J.,Mackie, Claire,Steckler, Thomas

, p. 7243 - 7259 (2013/10/21)

Starting from a singleton chromanone high throughput screening (HTS) hit, we describe a focused medicinal chemistry optimization effort leading to the identification of a novel series of phenoxymethyl-dihydrothiazolopyridone derivatives as selective positive allosteric modulators (PAMs) of the metabotropic glutamate 5 (mGlu5) receptor. These dihydrothiazolopyridones potentiate receptor responses in recombinant systems. In vitro and in vivo drug metabolism and pharmacokinetic (DMPK) evaluation allowed us to select compound 16a for its assessment in a preclinical animal screen of possible antipsychotic activity. 16a was able to reverse amphetamine-induced hyperlocomotion in rats in a dose-dependent manner without showing any significant motor impairment or overt neurological side effects at comparable doses. Evolution of our medicinal chemistry program, structure activity, and properties relationships (SAR and SPR) analysis as well as a detailed profile for optimized mGlu5 receptor PAM 16a are described.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 35370-80-0