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2-amino-3-(3-fluorophenyl)propan-1-ol, commonly known as 3-F-APINACA, is a synthetic cannabinoid belonging to the indazole-3-carboxamide class. It is a potent agonist of the CB1 receptor and exhibits psychoactive properties, causing intense euphoria, altered perception, and hallucinations when used recreationally. However, it has been associated with adverse effects and overdose cases, leading to its classification as a controlled substance in many jurisdictions.

35373-68-3

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35373-68-3 Usage

Uses

Used in Controlled Substances Regulation:
3-F-APINACA is used as a controlled substance in various jurisdictions due to its potential for abuse and harmful effects. Its use and distribution are strictly regulated to prevent misuse and protect public health.
Used in Research and Toxicology Studies:
3-F-APINACA serves as a subject of research in toxicology and pharmacology, helping scientists understand the mechanisms of action and potential risks associated with synthetic cannabinoids. This knowledge aids in the development of policies and regulations to mitigate their harmful effects.
Used in Forensic Analysis:
In forensic analysis, 3-F-APINACA is identified and analyzed to determine its presence in cases of drug abuse, overdose, or poisoning. This helps in the investigation and prosecution of illegal activities related to the production, distribution, and use of synthetic cannabinoids.
Note: It is important to clarify that 3-F-APINACA is not approved for medical or recreational use due to its potential for abuse and harmful effects. The mentioned uses are related to its classification, research, and forensic analysis.

Check Digit Verification of cas no

The CAS Registry Mumber 35373-68-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,3,7 and 3 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 35373-68:
(7*3)+(6*5)+(5*3)+(4*7)+(3*3)+(2*6)+(1*8)=123
123 % 10 = 3
So 35373-68-3 is a valid CAS Registry Number.

35373-68-3Upstream product

35373-68-3Downstream Products

35373-68-3Relevant academic research and scientific papers

Nucleophilic RhI Catalyzed Selective Isomerization of Terminal Aziridines to Enamides

Tian, Yingying,Kunz, Doris

, p. 4272 - 4275 (2020/07/04)

The selective isomerization of various terminal N-Boc protected aziridines to enamides was realized using the highly reactive nucleophilic rhodium catalyst C with the Lewis acid LiNTf2 as co-catalyst under moderate conditions. The reaction proceeds smoothly with only 1 molpercent catalyst loading and excellent yields were achieved. An intermediate containing an enamide with a non-conjugated terminal C=C double bond was detected during the course of the reaction, which isomerizes to form the thermodynamically favored 2-amido styrene. Mechanistic insight is gained based on these observations.

Synthesis and biological evaluation of 3-(2-aminoethyl) uracil derivatives as gonadotropin-releasing hormone (GnRH) receptor antagonists

Kim, Seon-Mi,Lee, Minhee,Lee, So Young,Lee, Soo-Min,Kim, Eun Jeong,Kim, Jae Sun,Ann, Jihyae,Lee, Jiyoun,Lee, Jeewoo

, p. 413 - 424 (2018/01/17)

We investigated a series of uracil analogues by introducing various substituents on the phenyl ring of the N-3 aminoethyl side chain and evaluated their antagonistic activity against human gonadotropin-releasing hormone (GnRH) receptors. Analogues with su

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