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Amphotericin B, methyl ester hydrochloride is a chemical compound derived from amphotericin B, a potent polyene antifungal medication with a broad spectrum of activity against various fungi. The incorporation of the methyl ester hydrochloride group into the amphotericin B molecule significantly improves its solubility and bioavailability, thereby enhancing its clinical effectiveness in treating fungal infections.

35375-29-2

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35375-29-2 Usage

Uses

Used in Pharmaceutical Industry:
Amphotericin B, methyl ester hydrochloride is used as an antifungal agent for the treatment of serious fungal infections. Its enhanced solubility and bioavailability make it more effective in combating infections caused by various types of fungi.
Used in the Treatment of Invasive Candidiasis:
Amphotericin B, methyl ester hydrochloride is employed as a therapeutic agent for the treatment of invasive candidiasis, a severe systemic fungal infection caused by Candida species. Its broad-spectrum antifungal activity and improved pharmacokinetic properties contribute to its effectiveness in managing this condition.
Used in the Treatment of Cryptococcal Meningitis:
AMPHOTERICIN B, METHYL ESTER HYDROCHLORIDE is also used as a treatment for cryptococcal meningitis, a life-threatening fungal infection of the central nervous system caused by Cryptococcus neoformans. The enhanced solubility and bioavailability of amphotericin B, methyl ester hydrochloride, allow for better penetration into the central nervous system, improving the treatment outcomes for patients with this condition.
Used in the Management of Other Systemic Fungal Infections:
Amphotericin B, methyl ester hydrochloride is utilized in the management of other systemic fungal infections that are resistant to conventional antifungal treatments. Its broad-spectrum activity and improved pharmacological properties make it a valuable option for treating a wide range of fungal infections, including those caused by Aspergillus, Histoplasma, and Blastomyces species.

Check Digit Verification of cas no

The CAS Registry Mumber 35375-29-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,3,7 and 5 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 35375-29:
(7*3)+(6*5)+(5*3)+(4*7)+(3*5)+(2*2)+(1*9)=122
122 % 10 = 2
So 35375-29-2 is a valid CAS Registry Number.

35375-29-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl (1S,3R,4E,6E,8E,10E,12E,14E,16E,18S,19R,20R,21S,25R,27R,30R,31R,33S,35R,37S,38R)-3-[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-19,25,27,30,31,33,35,37-octahydroxy-18,20,21-trimethyl-23-oxo-22,39-dioxabicyclo[33.3.1]nonatriaconta-4

1.2 Other means of identification

Product number -
Other names Amphotericin B,methyl ester,hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:35375-29-2 SDS

35375-29-2Upstream product

35375-29-2Downstream Products

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