353794-07-7

Upstream product

• 369-34-6 3,4-difluoronitrobenzene 
• 121873-01-6 6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid ethyl ester 

Downstream Products

• 353794-08-8 6,7-difluoro-1-(2-fluoro-4-nitrophenyl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid 
• 631898-37-8 ethyl 6-fluoro-1-(2-fluoro-4-nitrophenyl)-1,4-dihydro-4-oxo-7-(piperazin-1-yl)quinoline-3-carboxylate 
• 631898-44-7 6-fluoro-(2-fluoro-4-nitrophenyl)-1,4-dihydro-4-oxo-7-(piperazin-1-yl)oxoquinoline-3-carboxamide 
• 353794-09-9 6-fluoro-(2-fluoro-4-nitrophenyl)-1,4-dihydro-4-oxo-7-(piperazin-1-yl)oxoquinoline-3-carboxylic acid 
• 353794-13-5 1-(4-nitro-2-fluorophenyl)-6-fluoro-7-{4-[2-(4-methoxyphenyl)-2-oxoethyl]-1-piperazinyl}-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 
• 353794-14-6 1-(4-amino-2-fluorophenyl)-6-fluoro-7-{4-[2-(4-methoxy-phenyl)-2-oxoethyl]-1-piperazinyl}-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 

Relevant academic research and scientific papers

Synthesis and antibacterial evaluation of certain quinolone derivatives

A number of 7-substituted quinolone derivatives were synthesized and evaluated for antibacterial and cytotoxic activities. Preliminary results indicated that most compounds tested in this study demonstrated better activity against methicillin-resistant St