35400-43-2 Usage
Chemical Properties
Different sources of media describe the Chemical Properties of 35400-43-2 differently. You can refer to the following data:
1. Tan colored liquid; sulfide odor. Soluble in organic solvents; insoluble in water.
2. Sulprofos is a tan colored liquid.
Uses
Different sources of media describe the Uses of 35400-43-2 differently. You can refer to the following data:
1. Insecticide.
2. Sulprofos is used to control Lepidoptera, thrips and other insects in
cotton, soya, tobacco, vegetables and tomatoes.
3. Sulprofos is a component of an inventive pesticide water dispersible granule used for preventing and controlling scale insect of tobacco and has advantages of obvious synergistic effect, environmental protection, good pest control effect, less usage amount and low insecticide resistance.
General Description
Tan-colored liquid with a sulfide-like odor.
Safety Profile
Poison by ingestion. Moderately toxic by skin contact. When heated to decomposition it emits very toxic fumes of POx and SOx.
Potential Exposure
A potential danger to those involved in the manufacture, formulation, and application of this insecticide that is used for control of certain lepidopterous, dipterous, and hemipterous insects on cotton, etc.
Environmental Fate
Biological. From the first-order biotic and abiotic rate constants of sulprofos in estu-
arine water and sediment/water systems, the estimated biodegradation half-lives were
19.5–61.6 and 3.5–19 days, respectively (Walker et al., 1988).Photolytic. When sulprofos was exposed to sunlight as deposits on cotton foliage, glass
surfaces and in aqueous solution, the insecticide degraded rapidly (half-life <2 days).
Irradiation of sulprofos in aqueous solution using UV light (λ >290Chemical/Physical. Emits toxic oxides of sulfur and phosphorus when heated to
decomposition (Lewis, 1990).
Metabolic pathway
Sulprofos is an organophosphorus insecticide possessing a 4-(methylthio)
phenyl group and as such its metabolic fate has much in common
with fenthion with which it also has the phosphorothioate (P=S) group in
common. The major route of sulprofos metabolism is by oxidation to the
sulfoxide and more slowly to the sulfone. The additional route of bioactivation
is through oxidative desulfuration to form the sulprofos oxon
and all five oxidative metabolites (sulprofos sulfoxide, sulprofos sulfone,
sulprofos oxon, sulprofos oxon sulfoxide and sulprofos oxon sulfone)
have been detected in rats. Degradative metabolism by hydrolysis or oxidative
dearylation to the phenols occurs rapidly. Stage II metabolism in
mammals involves the rapid conjugation of the phenolic dearylation
products. The fate of the S-propyl phosphorodithioate group has not
apparently been reported.
Metabolism
Major metabolic routes
are by oxidation to the sulfoxide and sulfone and oxidative
desulfuration to the oxons. Detoxification by dearylation
to the phenols occurs rapidly. Sulprofos is degraded in soil
with a half-life ranging from a few days to several weeks,
depending on the soil type.
Toxicity evaluation
The acute
oral LD50 for rats is 176–304 mg/kg. Inhalation LC50
(4 h) for rats is >4.1 mg/L air. NOEL (2 yr) for rats is
6 mg/kg diet (0.3 mg/kg/d). ADI is 3 μg/kg b.w. Sulprofos
administered to rats is rapidly metabolized, and 92% of
the dose is excreted within 24 h.
Degradation
The half-lives in aqueous solution at pH values 4,7 and 9 were 26,151 and
51 days, respectively. Its DT50 was less than two days when a thin film
was exposed to sunlight. Ivie and Bull (1976), examined the photodecomposition
in sunlight of sulprofos on cotton leaves, glass surfaces
and aqueous solutions. The major metabolites were sulprofos sulfoxide
(2) and sulfone (3), with minor amounts of sulprofos oxon sulfoxide (4)
and the three possible phenolic hydrolysis products (5, 6 and 7). Photodecomposition
is thus via thiooxidation, oxidative desulfuration and
cleavage of the P-O-aryl group as shown in Scheme 1. A large number of
minor photolysis products which could not be identified were also
formed.
Check Digit Verification of cas no
The CAS Registry Mumber 35400-43-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,4,0 and 0 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 35400-43:
(7*3)+(6*5)+(5*4)+(4*0)+(3*0)+(2*4)+(1*3)=82
82 % 10 = 2
So 35400-43-2 is a valid CAS Registry Number.
InChI:InChI=1/C12H19O2PS3/c1-4-10-18-15(16,13-5-2)14-11-6-8-12(17-3)9-7-11/h6-9H,4-5,10H2,1-3H3
35400-43-2Relevant articles and documents
Insecticidal composition for agricultural and horticultural use
-
, (2008/06/13)
A synergistic insecticidal composition comprising a nitromethylene derivative of the formula STR1 in which X is a lower alkyl group, a lower alkoxy group or a halogen atom, n is 0, 1 or 2, and m is 2 or 3, and an insecticide which is a carboxylic acid ester, carbamate, organophosphate ester or one of a group of specific compounds.
