3543-42-8

Basic information

• Product Name: 2-hexanone, 3-(phenylmethylene)-
• Synonyms: 3-Benzylidenehexan-2-one
• CAS NO: 3543-42-8
• Molecular Formula: C₁₃H₁₆O
• Molecular Weight: 188.2655
• Mol File: 3543-42-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 302.285°C at 760 mmHg
• Flash Point: 111.185°C
• Density: 0.974g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.539
• CAS DataBase Reference: 2-hexanone, 3-(phenylmethylene)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hexanone, 3-(phenylmethylene)-(3543-42-8)
• EPA Substance Registry System: 2-hexanone, 3-(phenylmethylene)-(3543-42-8)

Safety Data

• Hazardous Substances Data: 3543-42-8(Hazardous Substances Data)

Upstream product

• 591-78-6 n-hexan-2-one 
• 100-52-7 benzaldehyde 
• 319923-38-1 1-phenyl-2-propyl-3-butyn-1-ol 
• 925-90-6 ethylmagnesium bromide 
• 94348-75-1 4-acetoxy-3-methylene-4-phenylbutan-2-one 

Downstream Products

• 299922-02-4 5-oxo-3-phenyl-4-propyl-cyclohexane-1,1,2,2-tetracarbonitrile 
• 1101197-83-4 (S)-3-benzyl-2-hexanone 
• 4904-40-9 2-propyl-1t-phenyl-buten-⁽¹⁾-one-⁽³⁾-oxime 
• 77124-15-3 (E)-3-phenyl-2-propyl-prop-2-enoic acid 

Relevant articles and documents

Highly enantioselective synthesis of optically active ketones by iridium-catalyzed asymmetric hydrogenation

(Chemical Equation Presented) Close to perfect enantioselectivity (up to 99% ee, see scheme) is found for the formation of α-substituted ketones by the asymmetric hydrogenation of enones with an iridium-phosphinooxazoline catalyst. In an operationally simple process, both linear and cyclic substrates react well and afford the desired products in high yields. A wide variety of substituents are tolerated, thus making the method synthetically appealing.

Double Michael addition reactions of some new 1,5-diaryl-2-alkyl-1,4-pentadien-3-ones: Part II

The reactivity of unsymmetrical 1,5-diaryl-2-alkyl-l,4-pentadien-3-ones with active methylene compounds has been studied. The structures of the compounds have been established by spectral parameters.