3543-46-2 Usage
General Description
5-Bromo-4-phenylpyrimidine is a chemical compound with the molecular formula C10H7BrN2. It is a heterocyclic organic compound composed of a pyrimidine ring substituted with a bromine atom at the 5-position and a phenyl group at the 4-position. 5-Bromo-4-phenylpyrimidine is commonly used as a building block in organic synthesis, particularly in the pharmaceutical industry, for the production of various pharmaceutical drugs and intermediates. Its structure and reactivity make it a versatile tool for the synthesis of a wide range of different compounds, and it is often used as a key intermediate in the development of new pharmaceuticals. Additionally, 5-Bromo-4-phenylpyrimidine is also utilized in research laboratories for the development of new chemical processes and materials.
Check Digit Verification of cas no
The CAS Registry Mumber 3543-46-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,5,4 and 3 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 3543-46:
(6*3)+(5*5)+(4*4)+(3*3)+(2*4)+(1*6)=82
82 % 10 = 2
So 3543-46-2 is a valid CAS Registry Number.
3543-46-2Relevant articles and documents
Metal free C-H functionalization of diazines and related heteroarenes with organoboron species and its application in the synthesis of a CDK inhibitor, meriolin 1
Thatikonda, Thanusha,Singh, Umed,Ambala, Srinivas,Vishwakarma, Ram A.,Singh, Parvinder Pal
, p. 4312 - 4320 (2016/05/24)
Here, we report a metal-free cross-coupling reaction of diazines and related heteroarenes with organoboron species via C-H functionalization. The optimized conditions represent a metal-free method for the activation of aryl/heteroarylboronic acids, which undergo coupling with diazines and related heteroarenes. Optimized conditions also find application in the synthesis of a pyrimidine-based potent CDK inhibitor, meriolin1.
INVESTIGATION OF SOME ELECTROPHILIC REACTIONS OF 4-PHENYL-5-HYDROXYPYRIMIDINE AND ITS 1-OXIDE
Gashev, S. B.,Sedova, V. F.,Smirnov, L. D.,Mamaev, V. P.
, p. 1008 - 1012 (2007/10/02)
A difference in the reactivities of the 2 and 6 positions of the 5-hydroxypyrimidine ring and an effect of the N-oxide group on the direction of electrophilic substitution reactions were demonstrated in the case of synthesized 4-phenyl-5-hydroxypyrimidine and its 1-oxide.