35436-69-2Relevant academic research and scientific papers
HIV-1 PROTEASE TRANSITION STATE AND USES THEREOF
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Paragraph 0035, (2013/09/12)
Methods and systems for obtaining inhibitors of human immunodeficiency virus- 1 (HIV-1) protease are disclosed where the methods involve designing compounds that resemble the HIV-1 protease transition state.
Isotope effects in oxidative deamination of L-phenylalanine
Kanska, Marianna,Skowera, Katarzyna
body text, p. 443 - 444 (2011/05/06)
The mechanism of reversible oxidative deamination of L-phenylalanine into phenylpyruvic acid catalyzed by enzyme L-Phenylalanine Dehydrogenase (EC 1.4.1.20) using kinetic and solvent isotope effects was studied. Copyright
Synthesis of tritium labeled isotopomers of L-tyrosine
Augustyniak,Suchecki,Jemielity,Kanski,Kanska
, p. 559 - 567 (2007/10/03)
The synthesis of four selectively labeled isotopomers of L-tyrosine, (L-Tyr), using chemical and enzymatic methods is reported. Four tritium labeled isotopomers of L-phenylalanine (L-Phe) - [2-3H]-, [2′,6′-3H2]-, [3R-3H]- and [3S-3H]- have been synthesized using a combination of chemical and enzymatic methods. The labeled isotopomers of L-Phe have been converted into [2-3H]-, [2′,6′-3H2]-, [3R-3H]-, and [3S-3H]-L-Tyr by using the enzyme L-phenyl-alanine 4′-monooxygenase. Copyright
