3544-13-6

Upstream product

• 626-17-5 benzene-1,3-dicarbonitrile 
• 176636-07-0 2,2'-bis(tributylstannyl)-5,5'-m-phenylenebis(tetrazole) 

Downstream Products

• 191339-66-9 1,3-Bis[2-(6-bromohexyl)tetrazol-5-yl]benzene 
• 191339-65-8 1,3-Bis[2-(8-bromooctyl)tetrazol-5-yl]benzene 
• 1187328-22-8 1,3-bis[2-(7-bromoheptyl)tetrazol-5-yl]benzene 
• 1187328-23-9 1,3-bis[2-(9-bromononyl)tetrazol-5-yl]benzene 
• 1354833-31-0 1,2-bis{5-[3-(2-vinyl-2H-tetrazol-5-yl)phenyl]-2H-tetrazol-2-yl}ethane 

Relevant academic research and scientific papers

Two SrII coordination compounds based on tetrazole-carboxylate ligands

Two novel coordination compounds, [Sr(atzp)2(H2O)2]·CH3OH (1) and [Sr(dtzpha)(H2O)3]·4H2O (2) [Hatzp=5-aminotetrazole-1-propionic acid, H2dtzpha=1,3-di(tetrazol-5-yl)benzene-N2,N2'-diacetic acid)], have been generated by using 5-aminotetrazole-1-propionic acid and 1,3-di(tetrazol-5-yl)benzene-N2,N2'-diacetic acid to react with strontium salts, respectively. X-ray diffraction analysis reveals that carboxylic groups of two ligands show the same coordination mode (the μ1,1,3-COO coordination mode), compound 1 displays a 1D structure while compound 2 shows a 2D structure, which implies the influence of the number of the carboxylic acid groups. Luminescence properties of 1 and 2 were investigated at room temperature in the solid state.

Reactions of bis(tetrazole)phenylenes. Surprising formation of vinyl compounds from alkyl halides

The reactions of 1,2-bis(tetrazol-5-yl)benzene (1), 1,3-bis(tetrazol-5-yl) benzene (2), 1,4-bis(tetrazol-5-yl)benzene (3), 1,2-(Bu3SnN 4C)2C6H4 (4), 1,3-(Bu 3SnN4C)2C

Biosynthesis of Pd/MnO2 nanocomposite using Solanum melongena plant extract and its application for the one-pot synthesis of 5-substituted 1H-tetrazoles from aryl halides

In this work, for the first time, Solanum melongena plant extract was used for the green synthesis of Pd/MnO2 nanocomposite via reduction osf Pd(II) ions to Pd(0) and their immobilization on the surface of manganese dioxide (MnO2) nanoparticles (NPs) as an effective support. The synthesized nanocomposite were characterized by various analytical techniques such as Fourier transform infrared (FT-IR), X-ray diffraction (XRD), transmission electron microscopy (TEM), field emission scanning electron microscopy (FESEM), energy dispersive X-ray spectroscopy (EDS) and UV–Vis spectroscopy. The catalytic activity of Pd/MnO2 nanocomposite was used as a heterogeneous catalyst for the one-pot synthesis of 5-substituted 1H-tetrazoles from aryl halides containing various electron-donating or electron-withdrawing groups in the presence of K4[Fe (CN)6] as non-toxic cyanide source and sodium azide. The products were obtained in good yields via a simple methodology and easy work-up. The nanocatalyst can be recycled and reused several times with no remarkable loss of activity.

Antimicrobial evaluation of 5-substituted aryl 1H-tetrazoles

Background: Tetrazole derivatives such as 1-substituted dinitrobenzyl tetrazoles and their oxa and selanyl analogs have previously been studied against drug-susceptible and multidrugresistant mycobacteria. In addition, other tetrazole derivatives have bee

Synthesis of 5-substituted 1H-tetrazoles from aryl halides using nanopolymer-anchored palladium(II) complex as a new heterogeneous and reusable catalyst

Abstract: This paper reports on the preparation and use of chloromethylated polystyrene-anchored palladium(II) complex, [Ps-ttet-Pd(II)], as a separable nanocatalyst for the synthesis of 5-substituted 1H-tetrazoles by treating aryl halides with K4[Fe(CN)6] as non-toxic cyanide source, to generate in situ the corresponding aryl nitriles which then react through [2?+?3] cycloaddition with sodium azide. High yields of the products, simple methodology, easy work-up procedure, high catalytic activity, and superior cycling stability of the catalyst are the main advantages of this protocol. The structure of the catalyst was characterized using the powder XRD, SEM, TG-DTA, EDS, AAS, and FT-IR spectroscopy techniques. Graphical abstract: [Figure not available: see fulltext.]

Microwave Synthesis of 5-Substituted 1 H-Tetrazoles Catalyzed by Bismuth Chloride in Water

(Chemical Equation Presented). Bismuth chloride was used to catalyze the [2 + 3] cycloaddition between sodium azide with aryl nitriles, aliphatic nitriles, and vinyl nitriles. A number of 5-substituted 1H-tetrazoles were synthesized in water or isopropano

Self-healing and moldable material with the deformation recovery ability from self-assembled supramolecular metallogels

A self-assembled non-covalent metallogel system with self-healing, deformation recoverable, moldable and bottom-up load-bearing properties was prepared using tetrazolyl derivatives and Pd(OAc)2. This journal is

Efficient transformation of inactive nitriles into 5-substituted 1 H-tetrazoles using microwave irradiation and their applications

Efficient transformations of inactive nitriles into 5-substituted 1H-tetrazoles in DMF in a microwave reactor are described. The present method is applied to the synthesis of tetrazolato-bridged dinuclear platinum(II) complex and tetrazole C1-ribonucleoside phosphoramidite. Georg Thieme Verlag Stuttgart, New York.

Tetranuclear complexes composed of dinickel(II) macrocyclic fragments bridged by 5,5′-(1,3-phenylene)bis-1H-tetrazolato and N,N-bis(tetrazol-5- ato)amine coligands: Synthesis, structures and magnetic properties

The dinuclear nickel(II) complex [Ni2LCl]+, where L2- represents a 24-membered macrocyclic hexamine-dithiophenolate ligand, reacts with 5,5′-(1,3-phenylene)bis-1H-tetrazole and N,N-bis(tetrazol-5-yl)amine to give the tetranuclear complexes [(Ni 2L)2(N4C-X-CN4)]+, where X = 1,3-C6H4 (1) and NH (2). The new complexes were both isolated as perchlorate or tetraphenylborate salts and characterized by elemental analysis, UV/Vis, IR spectroscopy, and X-ray analysis. The crystal structures of the tetraphenylborate salts show bridging bistetrazolato moieties joining two dinuclear [Ni2L]2+ fragments through their ring N2 and N3 atoms. Temperature-dependent magnetic susceptibility measurements reveal the presence of weak ferromagnetic exchange interactions between the NiII ions in the binuclear [Ni2L]2+ subunits with magnetic exchange coupling constant values of J1 = 16.6 cm -1 for 1[BPh4]2, and J1 = 16.8 cm-1 for 2[BPh4]2 (H = -2JS1S 2). The exchange coupling constant J2 across the bistetrazolato bridge in both compounds is less than 0.1 cm-1, which suggests that no significant interdimer coupling occurs across the linking tetrazolato moieties.

Kinetics of azidation of isomeric benzenedicarbonitriles

Rate constants and activation parameters of two-step azidation of isomeric dicyanobenzenes with dimethylammonium azide in DMF at 70-100°C were determined. Tetrazole rings are formed from cyano groups in dicyanobenzenes in a stepwise mode following the 1,3