35447-68-8

Usage

InChI:InChI=1/C5H9BrO/c1-4(2)3-5(6)7/h4H,3H2,1-2H3

Upstream product

• 503-74-2 3-methylbutyric acid 
• 590-86-3 isovaleraldehyde 

Downstream Products

• 16365-09-6 β-m-Nitro-phenoxy-ethyl-isovalerat 
• 108-64-5 Ethyl isovalerate 
• 66582-16-9 3-methylbutanoyl cyanide 
• 5633-85-2 2,7-dimethyl-octane-4,5-dione 
• 35158-25-9 2-isopropyl-5-methyl-hex-2-enal 
• 590-86-3 isovaleraldehyde 
• 150272-54-1 4-chlorophenyl 3-methylbutanoate 
• 103-38-8 benzyl isovalerate 
• 2364-50-3 isovaleranilide 
• 549516-52-1 N,N-dibenzyl-3-methylbutanamide 
• 98379-78-3 3-methyl-N-benzylbutyramide 
• 16204-62-9 1-mesityl-3-methyl-but-1-ene 
• 16204-64-1 2¹-oxy-1.3.5-trimethyl-2-isopentyl-benzene 
• 16204-65-2 1-isopropenyl-2,4,6-trimethylbenzene 

Relevant academic research and scientific papers

Aerobic oxidative esterification and thioesterification of aldehydes using dibromoisocyanuric acid under mild conditions: No metal catalysts required

A practical direct method for the direct preparation of esters and thioesters from aldehydes is described. Esters and thioesters were synthesized by oxidative esterification and thioesterification via in situ generated acyl bromide intermediates, which were used to react with various alcohols and thiols. The esterification and thioesterification were readily performed in the presence of dibromoisocyanuric acid in dichloromethane, without any metal catalysts and under mild conditions. By using this reaction protocol, various esters and thioesters were prepared in high yields. This effective method offers a promising approach for the facile esterification and thioesterification of aldehydes.

Convenient metal-free direct oxidative amidation of aldehyde using dibromoisocyanuric acid under mild conditions

A facile method for the direct synthesis of amides from aldehydes is described. Amide bonds were synthesized by an oxidative amidation in the presence of dibromoisocyanuric acid (DBI). Treatment of aromatic and aliphatic aldehydes with dibromoisocyanuric acid generated acyl bromide intermediates, which were employed to react with a variety of secondary and primary amines to give amides. Through this reaction method, various amides were synthesized directly from aldehydes under mild conditions in high yields and short times. This facile and efficient procedure provides potential strategy for the direct synthesis of amides from aldehydes.