354538-35-5

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 354538-32-2 (1R)-1-(N-tosyl-6-bromoindol-3-yl)-1-azido-2-[(tert-butyldimethylsilyl)oxy]ethane 
• 354538-30-0 (1S)-1-(N-tosyl-6-bromoindol-3-yl)-2-[(tert-butyldimethylsilyl)oxy]-1-ethanol 
• 354538-34-4 (R)-2-azido-2-(N-tosyl-6-bromoindol-3-yl)-1-ethanol 
• 354538-26-4 (S)-1-(N-tosyl-6-bromoindol-3-yl)-1,2-ethanediol 
• 158991-81-2 6-bromo-N-(1-p-toluenesulphonyl)-indole-3-carboxaldehyde 
• 17826-04-9 6-bromo-1H-indole-3-carbaldehyde 
• 24424-99-5 di-tert-butyl dicarbonate 
• 936824-55-4 tert-butyl (1R',5S'')-{1-(1'-acetyl-6'-bromoindol-3'-yl)-2-oxo-2-(2''-oxo-5''-phenyl-3'',1''-oxazolidinyl)}ethylcarbamate 
• 936824-49-6 (1'R,5''S)-1-acetyl-6-bromo-3-{1'-azido-2'-oxo-2'-(2''-oxo-5''-phenyl-3'',1''-oxazolidinyl)ethyl}indole 
• 936824-50-9 tert-butyl (R)-{1-(6'-bromoindol-3'-yl)-2-hydroxy}ethylcarbamate 
• 354538-27-5 6-bromo-1-tosyl-3-vinyl-1H-indole 

Downstream Products

• 354538-23-1 (R)-6-bromo-N-[(N-tosyl-6-bromoindol-3-yl)azidoethyl]-α-oxoindole-3-acetamide 
• 354538-37-7 (R)-3-(6-bromoindol-3-yl)-6-(N-tosyl-6-bromoindol-3-yl)-5,6-dihydro-2(1H)-pyrazinone 
• 1026187-62-1 2-azido-1-[6-bromo-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-ethylamine 
• 936824-56-5 (R)-2-(6''-bromoindol-3''-yl)-{N-2'-(6'''-bromo-1'''-tosylindol-3'''-yl)-2'-(tert-butoxycarbonylamino)ethyl}-2-oxoethanamide 
• 354538-36-6 (1R)-N-(tert-butyloxycarbonyl)-1-(N-tosyl-6-bromoindol-3-yl)-2-azidoethylamine 

Relevant academic research and scientific papers

Total synthesis of marine bisindole alkaloid (+)-cis-dihydrohamacanthin B

The total synthesis of the marine bisindole alkaloid (+)-cis- dihydrohamacanthin B was achieved from optically pure (R)-indolylglycinol. Georg Thieme Verlag Stuttgart.

Enantioselective synthesis for the (-)-antipode of the pyrazinone marine alkaloid, hamacanthin A

A short enantioselective total synthesis for the (-)-antipode of the antifungal marine alkaloid, hamacanthin A, (6R)-3,6-bis(6-bromoindol-3-yl)-5,6-dihydro-2(1H)-pyrazinone, is described. This synthesis proceeds through the coupling of 3-indolyl-αoxoacetyl chloride and 3-indolyl azidoethylamine, followed by intramolecular aza-Wittig type cyclization. A concise and useful approach for the synthesis of (1R)-1-(indol-3-yl)-2-azidoethylamine using the Sharpless asymmetric dihydroxylation reaction followed by stereospecific azidation is also presented.