354565-68-7Relevant academic research and scientific papers
Using amide conformation to 'project' the stereochemistry of an (-)-ephedrine-derived oxazolidine: A pair of pseudoenantiomeric chiral amido-phosphine ligands
Clayden, Jonathan,Lai, Lai Wah,Helliwell, Madeleine
, p. 695 - 698 (2001)
Protection of a tertiary 2-formylbenzamide as an (-)-ephedrine-derived oxazolidine both forces the amide's stereogenic Ar-CO axis to adopt one of two possible diastereoisomeric conformations and protects the formyl group from attack during amide ortho-lit
Conformational preference in aromatic amides bearing chiral ortho substituents: Its origin and application to relayed stereocontrol
Betson, Mark S.,Clayden, Jonathan,Helliwell, Madeleine,Johnson, Paul,Lai, Lai Wah,Pink, Jennifer H.,Stimson, Christopher C.,Vassiliou, Neoclis,Westlund, Neil,Yasin, Samreen A.,Youssef, Latifa H.
, p. 424 - 443 (2007/10/03)
Tertiary aromatic amides bearing stereogenic centres ortho to the amide group may adopt two diastereoisomeric conformations which interconvert slowly on the NMR timescale at ambient temperature, and are therefore detectable by NMR. Certain classes of ster
