354578-83-9

Upstream product

• 106281-44-1 (6-oxocyclohex-1-en-1-yl)methyl acetate 
• 105956-40-9 2-(hydroxymethyl)cyclohex-2-en-1-one 
• 53723-51-6 1-cyclohexen-1-ylmethyl acetate 
• 930-68-7 cyclohexenone 

Downstream Products

• 354578-84-0 acetic acid 6-triisopropylsilanyloxy-cyclohex-1-enylmethyl ester 
• 354578-86-2 acetic acid 6-triphenylsilanyloxy-cyclohex-1-enylmethyl ester 
• 354578-85-1 (6-((tert-butyldimethylsilyl)oxy)cyclohex-1-en-1-yl)methyl acetate 
• 1436715-35-3 N-((6-((tertbutyldimethylsilyl)oxy)cyclohex-1-en-1-yl)methyl)-4-methyl-N-(3-phenylprop-2-yn-1-yl)-p-toluenesulfonamide 
• 1436715-84-2 C₂₉H₃₈BrNO₃SSi 
• 1436714-57-6 N-((6-hydroxycyclohex-1-en-1-yl)methyl)-4-methyl-N-(3-phenylprop-2-yn-1-yl)-p-toluenesulfonamide 
• 1436715-89-7 C₂₄H₃₇NO₃SSi 
• 1436713-80-2 (Z)-4-(fluoro(phenyl)methylene)-2-tosyl-1,2,3,4,4a,5,6,7-octahydroisoquinoline 
• 1436713-86-8 (Z)-4-(fluoro(p-tolyl)methylene)-2-tosyl-1,2,3,4,4a,5,6,7-octahydroisoquinoline 
• 1436713-91-5 (Z)-4-(fluoro(m-tolyl)methylene)-2-tosyl-1,2,3,4,4a,5,6,7-octahydroisoquinoline 
• 1436713-96-0 (Z)-4-(fluoro(naphthalen-1-yl)methylene)-2-tosyl-1,2,3,4,4a,5,6,7-octahydroisoquinoline 
• 1436714-01-0 (Z)-4-(fluoro(4-nitrophenyl)methylene)-2-tosyl-1,2,3,4,4a,5,6,7-octahydroisoquinoline 
• 1436714-06-5 (Z)-4-(fluoro(3-nitrophenyl)methylene)-2-tosyl-1,2,3,4,4a,5,6,7-octahydroisoquinoline 
• 1436714-11-2 (Z)-ethyl 4-(fluoro(2-tosyl-2,3,4a,5,6,7-hexahydroisoquinolin-4(1H)-ylidene)methyl)benzoate 

Relevant academic research and scientific papers

O 2-(6-Oxocyclohex-1-en-1-yl)methyl diazen-1-ium-1,2-diolates: A new class of nitric oxide donors activatable by GSH/GSTπ with both anti-proliferative and anti-metastatic activities against melanoma

The new nitric oxide (NO) donor O2-(6-oxocyclohex-1-en-1-yl)methyl diazen-1-ium-1,2-diolate 3c could simultaneously liberate NO as well as an active 3-glutathionyl-2-exomethylene-cyclohexanone 2 in the presence of GSH/GSTπ; exhibit potent antiproliferative activity; repress migration, invasion, and lateral migration of metastatic B16-BL6 cells; and significantly decrease hetero-Adhesion of B16-BL6 cells to human umbilical vein endothelial cells.

Transition-metal-free carbofluorination of TBS-protected nitrogen-containing cyclic enynols: Synthesis of fluorinated azabicycles

The synthesis of fluorinated azabicycles from tert-butyldimethylsilyl- protected N-containing cyclic enynols using inexpensive BF3· OEt2 is described. In this reaction, BF3 reacts as both the Lewis acid and the fluoride source for cyclization/fluorination of the TBS-protected cyclic N-containing enynols. The method provides an easy access to fluorinated azabicycles where a new C(sp2)-F bond and a new bicyclic skeleton are generated at ambient temperature within 1-13 min under metal-free reaction conditions.

Synthesis and comparative antibacterial activity of verdamicin C2 and C2a. A new oxidation of primary allylic azides in dihydro[2H]pyrans

(Chemical Equation Presented) A synthesis of verdamicin C2 and its congener C2a has been accomplished from sisomicin relying on a novel oxidative transformation of an allylic azide to the corresponding α,β- unsaturated aldehyde, and its stereocontrolled elaboration into the intended 5′ side chain of verdamicin C2 and C2a. In vitro antibacterial testing shows that both C6′ epimers in verdamicin C2 and C2a are equally active against a variety of bacterial strains. Oxidation of allylic primary azides, ethers, and esters of 2-substituted dihydro[2H]pyrans with SeO2 leads directly to the corresponding aldehydes.

Synthetic studies on lycopodium alkaloid, magellanine: Stereoselective construction of functionallized angular tricyclic skeletons by intramolecular Pauson-Khand reaction

Angular tricyclic compounds as intermediates for total synthesis of magellanine were synthesized by stereoselective Ireland-Claisen rearrangement and intramolecular Pauson-Khand reaction of exo-methylenecyclohexylalkynes. Interestingly, remarkably differe