354583-03-2

Upstream product

• 106-94-5 propyl bromide 
• 354583-02-1 (R)-1-(benzofuran-2-yl)-2-(p-toluenesulfonyl)aminopentane 
• 2013-12-9 D-norvaline 
• 62421-33-4 (R)-N-(p-toluenesulfonyl)-2-propylaziridine 
• 80696-30-6 (2R)-2-aminopentan-1-ol 
• 62421-32-3 (R)-2-amino-1-pentanol-bis-p-toluenesulfonate 

Downstream Products

• 260550-89-8 R-(-)-1-(benzofuran-2-yl)-2-propylaminopentane 

Relevant academic research and scientific papers

Enantioselective synthesis and absolute configuration of (-)-1-(benzofuran-2-yl)-2-propylaminopentane, ((-)-BPAP), a highly potent and selective catecholaminergic activity enhancer

Enantioselective synthesis and absolute configuration of (-)-1-(benzofuran-2-yl)-2-propylaminopentane ((-)-BPAP), which is a highly potent and selective catecholaminergic activity enhancer (CAE) substance, are described. The synthetic approach consists of the coupling reaction of benzofuran with (R)-N-tosyl-2-propylazirizine or (R)-N-methoxy-N-methylnorvaliamide, followed by appropriate modifications of the resulting coupling products. As the results, (-)-BPAP turned out to have the R configuration, which was finally confirmed by X-ray crystallographic analysis.