3546-51-8 Usage
Uses
Used in Pharmaceutical Industry:
2,4-dichloro-N-methylpyrimidin-5-amine is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs, contributing to the advancement of medicine.
Used in Agrochemical Industry:
In the agrochemical sector, 2,4-dichloro-N-methylpyrimidin-5-amine is utilized as an intermediate in the production of agrochemicals. Its role in this industry is vital for the creation of effective pesticides and other agricultural products that protect crops and enhance yields.
Used in Organic Compounds Production:
2,4-dichloro-N-methylpyrimidin-5-amine also serves as a building block in the synthesis of a wide range of organic compounds. Its versatility in chemical reactions makes it a valuable asset in the field of organic chemistry, leading to the development of new materials and compounds with various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 3546-51-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,5,4 and 6 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 3546-51:
(6*3)+(5*5)+(4*4)+(3*6)+(2*5)+(1*1)=88
88 % 10 = 8
So 3546-51-8 is a valid CAS Registry Number.
3546-51-8Relevant academic research and scientific papers
As tyrosine kinase inhibitors containing nitrogen and ring compound
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Paragraph 0272; 0276; 0277; 0278, (2017/04/26)
The invention belongs to the technical field of medicine, particularly relates to a heterocyclic nitrogen compound which acts as a tyrosine kinase inhibitor and is represented by a general formula (I) as well as a deuterated material, pharmaceutically acc
Approaching the active conformation of 1,3-diaminopyrimidine based covalent inhibitors of Bruton's tyrosine kinase for treatment of Rheumatoid arthritis
Huang, Zhenhua,Zhang, Qian,Yan, Lianzhong,Zhong, Guizhen,Zhang, Linqi,Tan, Xiaojuan,Wang, Yanli
, p. 1954 - 1957 (2016/04/05)
By applying conformational restrictions, we were able to discover highly potent 1,3-diaminopyrimidine based covalent inhibitors of BTK, such as 8a (IC50 = 3.76 nM), and providing useful information of its active conformation. We are developing these novel small molecule covalent inhibitors of BTK toward oral agents for Rheumatoid arthritis.
