35467-43-7

Basic information

• Product Name: (3β,16E)-16,17,18,19-Tetradehydro-17-methoxycorynan-16-carboxylic acid methyl ester
• Synonyms: (3β,16E)-16,17,18,19-Tetradehydro-17-methoxycorynan-16-carboxylic acid methyl ester;18,19-Didehydrohirsutine;Δ18-Hirsutine;(3-beta,16E)-16,17,18,19-Tetradehydro-17-methoxy-corynan-16-carboxylic acid methyl ester;Corynan-16-carboxylic acid, 16,17,18,19-tetradehydro-17-methoxy-, methyl ester, (3-beta,16E)-;Corynan-16-carboxylic acid, 16,17,18,19-tetrahydro-17-methoxy-, methyl ester, (3beta,16E)-;delta(Sup 18)-hirsutine;3-Epicorynantheine
• CAS NO: 35467-43-7
• Molecular Formula: C22H26N2O3
• Molecular Weight: 366.4534
• Mol File: 35467-43-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 533.2°Cat760mmHg
• Flash Point: 276.3°C
• Appearance: /
• Density: 1.22g/cm³
• Vapor Pressure: 1.89E-11mmHg at 25°C
• Refractive Index: 1.623
• PKA: 18.03±0.60(Predicted)
• CAS DataBase Reference: (3β,16E)-16,17,18,19-Tetradehydro-17-methoxycorynan-16-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (3β,16E)-16,17,18,19-Tetradehydro-17-methoxycorynan-16-carboxylic acid methyl ester(35467-43-7)
• EPA Substance Registry System: (3β,16E)-16,17,18,19-Tetradehydro-17-methoxycorynan-16-carboxylic acid methyl ester(35467-43-7)

Safety Data

• Hazardous Substances Data: 35467-43-7(Hazardous Substances Data)

Usage

General Description

"(3β,16E)-16,17,18,19-Tetradehydro-17-methoxycorynan-16-carboxylic acid methyl ester" is a complex chemical compound that belongs to the class of corynanthe alkaloids. It is a methyl ester derivative of corynanthe alkaloid, which is found in certain plants. (3β,16E)-16,17,18,19-Tetradehydro-17-methoxycorynan-16-carboxylic acid methyl ester has potential pharmacological properties and may have applications in the field of medicinal chemistry. However, further research is needed to fully understand its biological activities and potential therapeutic uses.

InChI:InChI=1/C22H26N2O3/c1-4-14-12-24-10-9-16-15-7-5-6-8-19(15)23-21(16)20(24)11-17(14)18(13-26-2)22(25)27-3/h4-8,13-14,17,20,23H,1,9-12H2,2-3H3/b18-13+/t14-,17-,20+/m0/s1

Upstream product

• 112547-46-3 {(2S,3S,12bS)-3-[2-(2-Nitro-phenylselanyl)-ethyl]-4-oxo-1,2,3,4,6,7,12,12b-octahydro-indolo[2,3-a]quinolizin-2-yl}-acetic acid tert-butyl ester 
• 112547-41-8 [(2S,3S,12bS)-3-(2-Hydroxy-ethyl)-4-oxo-1,2,3,4,6,7,12,12b-octahydro-indolo[2,3-a]quinolizin-2-yl]-acetic acid tert-butyl ester 
• 112547-42-9 ((2S,3S,12bS)-4-Oxo-3-vinyl-1,2,3,4,6,7,12,12b-octahydro-indolo[2,3-a]quinolizin-2-yl)-acetic acid tert-butyl ester 
• 112547-43-0 ((2S,3S,12bS)-3-Vinyl-1,2,3,4,6,7,12,12b-octahydro-indolo[2,3-a]quinolizin-2-yl)-acetic acid tert-butyl ester 
• 112547-38-3 C₁₇H₁₈N₂O₂ 
• 112547-37-2 C₁₇H₁₆N₂O₂ 
• 186581-53-3 diazomethane 
• 112547-44-1 3-Oxo-2-((2R,3S,12bS)-3-vinyl-1,2,3,4,6,7,12,12b-octahydro-indolo[2,3-a]quinolizin-2-yl)-propionic acid tert-butyl ester 

Downstream Products

• 50439-68-4 dihydrocorynantheine 

Relevant articles and documents

FIRST TOTAL SYNTHESIS OF (+/-)-HIRSUTEINE

First total synthesis of (+/-)-hirsuteine, 3β-epimer of corynantheine, was achieved via the route involving retro Michael and the subsequent Michael reaction of the furopyridone (2b).