35474-17-0Relevant academic research and scientific papers
A Mechanochemical-Assisted Oxidation of Amines to Carbonyl Compounds and Nitriles
Gaspa, Silvia,Porcheddu, Andrea,Valentoni, Antonio,Garroni, Sebastiano,Enzo, Stefano,De Luca, Lidia
, p. 5519 - 5526 (2017)
A mild, efficient, metal- and solvent-free oxidation of primary amines to aldehydes, ketones, and nitriles under ball-milling conditions is presented. This method has proved to be compatible with various functional groups and only requires easily accessible starting materials. Simple purification of the reaction mixtures by short-column chromatography afforded pure aldehydes, ketones, and nitriles as products.
