354820-63-6

Basic information

• Product Name: (S)-methyl 3-(3-amino-4-hydroxyphenyl)-2-((tert-butoxycarbonyl)amino)propanoate
• Synonyms: (S)-methyl 3-(3-amino-4-hydroxyphenyl)-2-((tert-butoxycarbonyl)amino)propanoate
• CAS NO: 354820-63-6
• Molecular Weight: 310.35
• Mol File: 354820-63-6.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: (S)-methyl 3-(3-amino-4-hydroxyphenyl)-2-((tert-butoxycarbonyl)amino)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-methyl 3-(3-amino-4-hydroxyphenyl)-2-((tert-butoxycarbonyl)amino)propanoate(354820-63-6)
• EPA Substance Registry System: (S)-methyl 3-(3-amino-4-hydroxyphenyl)-2-((tert-butoxycarbonyl)amino)propanoate(354820-63-6)

Safety Data

• Hazardous Substances Data: 354820-63-6(Hazardous Substances Data)

Upstream product

• 3195-65-1 methyl 3-nitro-L-tyrosinate 
• 621-44-3 3-nitro-L-tyrosine 
• 4326-36-7 (S)-N-(tert-butoxycarbonyl)tyrosine methyl ester 

Downstream Products

• 650141-45-0 C₂₃H₂₆N₂O₅ 
• 1305308-73-9 C₂₂H₂₄N₂O₅ 

Relevant articles and documents

Application of Nitroimidazole-Carbobane-Modified Phenylalanine Derivatives as Dual-Target Boron Carriers in Boron Neutron Capture Therapy

Boron neutron capture therapy (BNCT) has received extensive attention as noninvasive cell-level oncotherapy for treating solid cancer tumors. However, boron-containing drugs such as l-boronophenylalanine (BPA) and sodium borocaptate have low boron content

CONJUGATION LINKERS CONTAINING 2,3-DIAMINOSUCCINYL GROUP

Provided is a conjugate of a cytotoxic drug/molecule to a cell-binding molecule with a bis-linker (adual-linker) containing a 2, 3-diaminosuccinyl group. It also relates to preparation of the conjugate of a cytotoxic drug/molecule to a cell-binding molecule with the bis-linker, particularly when the drug having functional groups of amino, hydroxyl, diamino, amino-hydroxyl, dihydroxyl, carboxyl, hydrazine, aldehyde and thiol for conjugation with the bis-linker in a specific manner, as well as the therapeutic use of the conjugates.

Polyboron phenylalanine compound containing nitroimidazole, as well as preparation method and application thereof

The invention discloses a polyboron phenylalanine compound containing nitroimidazole as shown in a general formula (I) in the specification or pharmaceutically acceptable salt thereof, as well as a preparation method and application thereof. The compound