35490-76-7Relevant academic research and scientific papers
CINNOLINE DERIVATIVES AS AS BTK INHIBITORS
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Paragraph 0178-0179, (2013/10/21)
Disclosed are compounds of Formula 1, and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, and R5 are defined in the specification. The compounds are inhibitors of Bruton's tyrosine
Copper-catalyzed synthesis of 2-unsubstituted, N-substituted benzimidazoles
Hirano, Keiichi,Biju, Akkattu T.,Glorius, Frank
supporting information; experimental part, p. 9570 - 9572 (2010/03/24)
(Chemical Equation Presented) An efficient copper-catalyzed intramolecular arylation of formamidines forming 2-unsubstituted benzimidazoles in excellent yields is reported. Sixteen examples bearing sterically demanding substituents on nitrogen like Mes, 2,6-diisopropylphenyl, or 2-tert-butylphenyl and tolerating various functional groups demonstrate the utility of this method.
