35498-43-2Relevant academic research and scientific papers
Palladium-catalyzed amidation of 2-chloropyrimidines
Vimolratana, Marc,Simard, Jillian L.,Brown, Sean P.
experimental part, p. 1020 - 1022 (2011/03/20)
A mild and efficient Pd-catalyzed coupling of amides with 2-chloropyrimidines is described. The use of bidentate phosphines, such as Xantphos (7), as supporting ligands was found to be crucial for providing high yields of 2-(N-acylamino)pyrimidine couplin
