3550-06-9Relevant academic research and scientific papers
One-pot asymmetric conjugate addition-trapping of zinc enolates by activated electrophiles
Rathgeb, Xavier,March, Sebastien,Alexakis, Alexandre
, p. 5737 - 5742 (2007/10/03)
The copper-catalyzed asymmetric conjugate addition of dialkyl zinc leads to homochiral zinc enolates. These intermediates were trapped in situ with activated allylic electrophiles, without the need of additional palladium catalysis. High trans selectivity
Preparation et etude de nouveaux derives organozinciques allyliques fonctionnels
Lambert, Francois,Kirschleger, Bernard,Villieras, Jean
, p. 273 - 286 (2007/10/02)
Stable organozinc compounds derived from alkyl-3-alkyl-2-(bromomethyl)-propenoates have been prepared.NMR 13C, 1H and IR studies show only one Z stereoisomer (no methylenic form) with a strong chelation between zinc and the carbonyl oxygen of the ester and solvated by only one solvent molecule.Hydrolysis can be achieved by two concurrent mechanisms with or without transposition.
