355019-34-0Relevant academic research and scientific papers
Ring transformations of 2,3-dihydroisoxazoles via azomethine ylides - Formation of annulated 5- and 7-membered N-heterocycles
Friebolin, Wolfgang,Eberbach, Wolfgang
, p. 4349 - 4358 (2007/10/03)
On thermal activation the 2,3-dihydroisoxazoles 12-14 are transformed into annulated dihydroazepines 15-17 as main products, besides minor amounts of the corresponding pyrrole derivatives 18-20. In the proposed mechanism the azomethine ylides of type III and VI are involved as intermediates which undergo 1,5- and 1,7-ring closure reactions, respectively.
