35510-03-3

Usage

Uses

Used in Pharmaceutical Industry:
1,5-DIBROMO-2,4-BIS-BROMOMETHYL-BENZENE is used as a building block for the synthesis of various pharmaceuticals, contributing to the development of new drugs and improving the efficacy of existing medications.
Used in Agrochemical Industry:
In the agrochemical industry, 1,5-DIBROMO-2,4-BIS-BROMOMETHYL-BENZENE serves as a key intermediate in the production of agrochemicals, helping to create effective solutions for pest control and crop protection.
Used in Fine Chemicals Industry:
1,5-DIBROMO-2,4-BIS-BROMOMETHYL-BENZENE is utilized as a building block in the synthesis of fine chemicals, which are essential components in various industrial applications, including fragrances, dyes, and specialty chemicals.
Used in Specialty Polymers and Resins Production:
As an intermediate in the production of specialty polymers and resins, 1,5-DIBROMO-2,4-BIS-BROMOMETHYL-BENZENE plays a crucial role in developing high-performance materials with unique properties for use in various industries, such as automotive, aerospace, and electronics.

Upstream product

• 615-87-2 1,5-dibromo-2,4-dimethylbenzene 
• 108-38-3 m-xylene 
• 626-15-3 1,3-bis-(bromomethyl)benzene 

Downstream Products

• 1207737-34-5 C₃₆H₂₆ 
• 525-18-8 10,12-dihydroindeno<2,1-b>fluorene 
• 89767-79-3 3-[2,4-Dibromo-5-(2-carboxy-ethyl)-phenyl]-propionic acid 

Relevant academic research and scientific papers

Efficient Synthesis of Bis(dibromomethyl)arenes as Important Precursors of Synthetically Useful Dialdehydes

This work presents an efficient synthesis of bis(dibromomethyl)benzenes and a bis(dibromomethyl)thiophene as precursors of aromatic dialdehydes by bromination of dimethyl-substituted arenes under various reaction conditions (yields up to 99%). Several new variants of this reaction, including the use of N-bromosuccinimide (NBS) and bromine, and various solvents to replace carbon tetrachloride, benzene and carbon disulfide, were also tested. In the optimised protocols, the inconvenient solvents were replaced by 1,2-dichloroethane (DCE) and/or acetonitrile. In the DCE protocols, we reduced reaction times 24-32-fold, reduced the amount of NBS a fewfold and lowered power consumption relative to the literature protocols. The procedures also allowed elimination of long-lasting incandescent irradiation (100-500 W). The replacement of NBS by bromine led to a further reduction in the amount of brominating agent. The obtained bromo derivatives were efficiently converted into the corresponding dialdehydes (90-96%), which in turn are useful in materials chemistry.

Four- and Sixfold Tandem-Domino Reactions Leading to Dimeric Tetrasubstituted Alkenes Suitable as Molecular Switches

A highly efficient palladium-catalyzed fourfold tandem-domino reaction consisting of two carbopalladation and two C-H-activation steps was developed for the synthesis of two types of tetrasubstituted alkenes 3 and 6 with intrinsic helical chirality starting from substrates 1 and 4, respectively. A sixfold tandem-domino reaction was also developed by including a Sonogashira reaction. 20 compounds with different substitution patterns were prepared with yields of up to 97%. Structure elucidation by X-ray crystallography confirmed helical chirality of the two alkene moieties. Photophysical investigations of some of the compounds showed pronounced switching properties through light-controlled changes of their stereochemical configuration.

Meta-B-entacenes: New polycyclic aromatics incorporating two fused borepin rings

The synthesis of new boron-containing acenes (meta-B-entacenes) is reported. These compounds exhibit slightly non-planar core geometries with blue-shifted spectral properties and more negative electrochemical reduction potentials relative to known para is