355137-55-2Relevant academic research and scientific papers
An expeditious formal synthesis of (-)-epibatidine
Cabanal-Duvillard, Isabelle,Berrien, Jean-Francois,Royer, Jacques
, p. 2525 - 2529 (2000)
A short route to (-)-epibatidine is described. It includes a hetero-Diels-Alder reaction of a chiral non-racemic acyl-nitroso derivative and 2-t-butyldimethylsilyloxycyclohexadiene followed by chemical manipulations to furnish a known precursor of the natural product in 11% overall yield. Copyright (C) 2000 Elsevier Science Ltd.
