Welcome to LookChem.com Sign In|Join Free
  • or
4-(2-methylphenoxy)benzoic acid is an organic compound with the chemical formula C14H12O3. It is a white crystalline solid that is soluble in organic solvents and has a molecular weight of 228.24 g/mol. 4-(2-methylphenoxy)benzoic acid is characterized by the presence of a benzoic acid group (C6H5COOH) and a 2-methylphenoxy group (C6H4CH3O) attached to the 4-position of the benzene ring. It is used in various applications, including as an intermediate in the synthesis of pharmaceuticals and agrochemicals, due to its ability to form derivatives with potential biological activity. The compound's structure allows for a range of chemical reactions, such as esterification and amidation, which can lead to the development of new compounds with specific properties.

355154-50-6

Post Buying Request

355154-50-6 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

355154-50-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 355154-50-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,5,1,5 and 4 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 355154-50:
(8*3)+(7*5)+(6*5)+(5*1)+(4*5)+(3*4)+(2*5)+(1*0)=136
136 % 10 = 6
So 355154-50-6 is a valid CAS Registry Number.

355154-50-6Relevant academic research and scientific papers

Discovery of CS-2100, a potent, orally active and S1P3-sparing S1P1 agonist

Nakamura, Tsuyoshi,Asano, Masayoshi,Sekiguchi, Yukiko,Mizuno, Yumiko,Tamaki, Kazuhiko,Kimura, Takako,Nara, Futoshi,Kawase, Yumi,Shimozato, Takaichi,Doi, Hiromi,Kagari, Takashi,Tomisato, Wataru,Inoue, Ryotaku,Nagasaki, Miyuki,Yuita, Hiroshi,Oguchi-Oshima, Keiko,Kaneko, Reina,Watanabe, Nobuaki,Abe, Yasuyuki,Nishi, Takahide

scheme or table, p. 1788 - 1792 (2012/04/04)

S1P3-sparing S1P1 agonists have attracted attention as a suppressant of autoimmunity with reduced side effects. Our synthetic efforts and extensive SAR studies led to the discovery of 10b named CS-2100 with the EC50 value of 4.0 nM for human S1P1 and over 5000-fold selectivity against S1P3. The in vivo immunosuppressive efficacy was evaluated in rats on host versus graft reaction and the ID 50 value was determined at 0.407 mg/kg. The docking studies of CS-2100 with the homology model of S1P1 and S1P3 showed that the ethyl group on the thiophene ring of CS-2100 was sterically hindered by Phe263 in S1P3, not in the case of Leu276 in S1P1. This observation gives an explanation for the excellent S1P3-sparing characteristic of CS-2100.

Phenyl alkyleneoxy phenyl alkanoic acid esters

-

, (2008/06/13)

Pharmaceutical compositions having hypolipidaemic and/or hypoglycaemic activity, contain a substituted (4-carboxyphenoxy) phenyl alkane derivative.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 355154-50-6