35522-89-5Relevant academic research and scientific papers
Oxidation of Primary Alcohols and Aldehydes to Carboxylic Acids via Hydrogen Atom Transfer
Tan, Wen-Yun,Lu, Yi,Zhao, Jing-Feng,Chen, Wen,Zhang, Hongbin
supporting information, p. 6648 - 6653 (2021/09/08)
The oxidation of primary alcohols and aldehydes to the corresponding carboxylic acids is a fundamental reaction in organic synthesis. In this paper, we report a new chemoselective process for the oxidation of primary alcohols and aldehydes. This metal-free reaction features a new oxidant, an easy to handle procedure, high isolated yields, and good to excellent functional group tolerance even in the presence of vulnerable secondary alcohols and tert-butanesulfinamides.
PROCESS FOR THE PREPARATION OF SOTAGLIFLOZIN
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Page/Page column 44; 45, (2019/09/18)
Sotagliflozin may be prepared using schemes and intermediates disclosed herein. Sotagliflozin may be incorporated into pharmaceutical dosage forms for treatment of diabetes.
Catalytic oxidation of D-glucose derivatives with oxygen in alkali solutions in the presence of copper phenanthroline complexes
Borovko,Chernaya,Trusov
, p. 1952 - 1956 (2007/10/03)
Features of oxidation of model compounds, 1-O-methyl-D-glycoside and 1,2-O-isopropylidene-D-glucose, with oxygen in aqueous alkali solutions were studied to determine probable reaction centers in starch oxidation.
Selective oxidation of monosaccharide derivatives to uronic acids
Davis,Flitsch
, p. 1181 - 1184 (2007/10/02)
Primary hydroxyl groups in partially protected monosaccharide derivatives were selectively oxidised to carboxylic acids using sodium hypochlorite in the presence of catalytic amounts of 2,2,6,6-tetramethyl-1-piperidinyl oxy, free radical (TEMPO). Acetal,
Oxidation of partially protected carbohydrates at the nickel hydroxide electrode
Schaefer, Hans J.,Schneider, Roy
, p. 715 - 724 (2007/10/02)
Primary hydroxy groups in pyranoses are oxidized in excellent yields to the corresponding carboxylic acids. In furanose 3 the yield of acid is only moderate. Secondary hydroxy groups are inert, aside from lactols. The different reactivity of secondary and primary hydroxy groups allows the chemoselective oxidation of 8 and 10.
