35531-88-5

Basic information

• Product Name: CARINDACILLIN
• Synonyms: (2S,5R)-6α-[[3-[(2,3-Dihydro-1H-inden-5-yl)oxy]-1,3-dioxo-2-phenylpropyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2β-carboxylic acid;6α-[[3-(2,3-Dihydro-1H-inden-5-yl)oxy-1,3-dioxo-2-phenylpropyl]amino]penicillanic acid;Geopen-U;(2S,5R,6R)-6-[(3-indan-5-yloxy-3-keto-2-phenyl-propanoyl)amino]-7-keto-3,3-dimethyl-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;(2S,5R,6R)-6-[[3-(2,3-dihydro-1H-inden-5-yloxy)-3-oxo-2-phenyl-propanoyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;(2S,5R,6R)-6-[[3-(2,3-dihydro-1H-inden-5-yloxy)-3-oxo-2-phenylpropanoyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• CAS NO: 35531-88-5
• Molecular Formula: C26H26N2O6S
• Molecular Weight: 494.565
• Mol File: 35531-88-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 812.5°Cat760mmHg
• Flash Point: 445.2°C
• Appearance: /
• Density: 1.44g/cm³
• Vapor Pressure: 6.62E-28mmHg at 25°C
• Refractive Index: 1.68
• CAS DataBase Reference: CARINDACILLIN(CAS DataBase Reference)
• NIST Chemistry Reference: CARINDACILLIN(35531-88-5)
• EPA Substance Registry System: CARINDACILLIN(35531-88-5)

Safety Data

• Hazardous Substances Data: 35531-88-5(Hazardous Substances Data)

Usage

Uses

Antibacterial.

Therapeutic Function

Antibacterial

InChI:InChI=1/C26H26N2O6S/c1-26(2)20(24(31)32)28-22(30)19(23(28)35-26)27-21(29)18(15-7-4-3-5-8-15)25(33)34-17-12-11-14-9-6-10-16(14)13-17/h3-5,7-8,11-13,18-20,23H,6,9-10H2,1-2H3,(H,27,29)(H,31,32)/t18?,19-,20+,23-/m1/s1

Upstream product

• 551-16-6 6-Aminopenicillanic Acid 
• 27932-00-9 phenylmalonic acid mono-indan-5-yl ester 

Relevant articles and documents

Preparation, hydrolysis, and oral absorption of alpha-carboxy esters of carbenicillin.

Twelve alpha-carboxy esters of carbenicillin, a parenteral broad spectrum semisynthetic penicillin, were synthesized and examined as potential oral carbenicillin derivatives. The rates at which the esters were hydrolyzed in vitro to carbenicillin by animal and human tissues were compared and the carbenicillin serum levels arising after oral administration of the esters were measured in squirrel monkeys and human volunteer subjects. The alpha-carboxyphenyl ester of carbenicillin [carfecillin (British Pharmacopoeia approved name), BRL 3475] WAS SELECTED FOR FURTHER STUDY AND IS PRESENTLY UNDERGOING CLInical trial.