355378-65-3

Upstream product

• 38985-64-7 o-fluorophenyl isothiocyanate 

Downstream Products

• 374589-06-7 1-(4-chloro-phenyl)-3-[4-(2-fluoro-phenyl)-5-mercapto-4H-[1,2,4]triazol-3-yl]-6-methyl-1H-pyridazin-4-one 

Relevant academic research and scientific papers

Synthesis of pyridazinone-substituted 1,3,4-thiadiazoles, -1,3,4-oxadiazoles and -1,2,4-triazoles

Several 1-(1-aryl-1,4-dihydro-3-carboxy-6-methylpyridazin-4-one)-4-aryl thio-semicarbazides and their corresponding oxadiazole, thiadiazole and triazole derivatives were prepared and characterized by their spectral data. The preliminary biological tests showed that some new compounds exhibit good anti-fungal activity.

Synthesis and biological activity of 1,3,4-oxadiazole-substituted pyridazinones

Novel 3-(1,3,4-oxadiazol-2-yl)-1-aryl-6-methylpyridazin-4-ones have been synthesised by two methods. A preliminary bio-activity test showed that these compounds exhibit high antifungal activity.