355397-64-7

Usage

Uses

Used in Pharmaceutical Industry:
2,3-Bis(4-Fluorophenyl)Quinoxaline-6-Carboxylic Acid is used as a pharmaceutical candidate for its anticancer properties, targeting various types of cancer due to its ability to interact with biological systems at the molecular level. Its unique structure allows it to modulate cellular processes, potentially leading to the inhibition of tumor growth and progression.
Used in Antimicrobial Applications:
In the field of antimicrobials, 2,3-Bis(4-Fluorophenyl)Quinoxaline-6-Carboxylic Acid serves as an agent against various microorganisms, including bacteria and fungi, due to its ability to disrupt essential cellular functions, thereby inhibiting their growth and survival.
Used in Organic Electronics Industry:
2,3-Bis(4-Fluorophenyl)Quinoxaline-6-Carboxylic Acid is utilized as a charge transport material in the development of organic semiconductor devices, such as organic light-emitting diodes (OLEDs) and organic field-effect transistors (OFETs). Its electronic properties make it a promising candidate for enhancing the performance and efficiency of these devices.
Further research is ongoing to explore the potential applications and properties of 2,3-Bis(4-Fluorophenyl)Quinoxaline-6-Carboxylic Acid, with the aim of expanding its use across various industries and improving its efficacy and safety profile.

Upstream product

• 579-39-5 1,2-bis(4-fluorophenyl)ethane-1,2-dione 
• 619-05-6 3,4-diaminobenzoic acid 
• 36692-49-6 Methyl 3,4-diaminobenzoate 

Downstream Products

• 935293-21-3 C₃₅H₂₇F₂N₅O₅ 
• 835922-73-1 C₃₃H₂₄F₂N₄O₄ 
• 835922-78-6 C₃₃H₂₄F₂N₄O₃ 

Relevant academic research and scientific papers

QUINOXALINE COMPOUNDS AND USES THEREOF

This invention provides compounds of formula I and subsets thereof: wherein T, J, R, R4, Rq, o, RA, and RB and subsets thereof are as described in the specification. The compounds are inhibitors of NAMPT and are thus useful for treating cancer, inflammatory conditions, or T-cell mediated autoimmune disease.

Structure-activity relationship (SAR) studies of quinoxalines as novel HCV NS5B RNA-dependent RNA polymerase inhibitors

From chemical compound library screening using an HCV NS5B RNA-dependent RNA polymerase enzymatic assay, we identified a substituted quinoxaline hit with an IC50 of 5.5 μM. A series of substituted quinoxaline amide derivatives were synthesized

Wells-Dawson type heteropolyacid catalyzed synthesis of quinoxaline derivatives at room temperature

Wells-Dawson heteropolyacid (H6P2W18O 62 ? 24H2O) was used as an effective catalyst for the synthesis of biologically active quinoxaline derivatives from the condensation of o-phenylenediamines with 1,2-dicarbonyl compounds at room temperature in excellent yields. Springer-Verlag 2007.

Synthesis and reactivity of difluoroaromatic compounds containing heterocyclic central groups

The reaction of trichloroacetaldehyde with fluorobenzene, followed by a series of transformations, gave 4-fluorobenzil and 4,4′-difluorobenzil which were used in the synthesis of new difluoroaromatic compounds with a heterocyclic central group. The 1H, 13C, and 19F NMR spectra of the newly synthesized difluoroaromatic compounds were studied. The charge densities on the carbon atoms attached to fluorine were calculated in terms of the PM3 and AM1 semiempirical approximations. A correlation was found between the charge on C(F) and the corresponding 13C and 19F chemical shifts. Using this correlation, the reactivity of difluoroaromatic compounds in nucleophilic substitution reactions was estimated.