35544-29-7Relevant academic research and scientific papers
Why are benzimidazoles efficiently acylated with esters? Identification of a tetrahedral hemiacetal alkoxide intermediate
Asakawa, Ken-Ichi,Dannenberg,Fitch, Kenneth J.,Hall, Stan S.,Kadowaki, Chie,Karady, Sandor,Kii, Satoshi,Maeda, Kenji,Marcune, Benjamin F.,Mase, Toshiaki,Miller, Ross A.,Reamer, Robert A.,Tschaen, David M.
, p. 5081 - 5084 (2005)
2-Lithio benzimidazoles were acylated with esters, lactones, and lactams. The tetrahedral hemiacetal intermediates responsible for the efficient conversion were characterized by low temperature NMR.
