35556-06-0

Basic information

• Product Name: TILORONE ANALOG R11-877DA
• Synonyms: 1,1’-(2,8-dibenzothiophenediyl)bis(2-(dimethylamino)-ethanondihydrochlorid;1,1’-(2,8-dibenzothiophenediyl)bis(2-(dimethylamino)ethanone)dihydrochloride;e,trihydrate;rmi11877da;trihydrate;TILORONE ANALOG R11-877DA;dibenzothiophene-2,8-diylbis((N-carbonylmethylene)dimethylamine) dihydrochloride trihydrate;2,8-Bis(dimethylaminoacetyl)dibenzothiophene dihydrochloride trihydrate
• CAS NO: 35556-06-0
• Molecular Formula: C₂₀H₂₂N₂O₂S*2ClH
• Molecular Weight: 481.438
• EINECS: 252-616-6
• Mol File: 35556-06-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 531.4°Cat760mmHg
• Flash Point: 275.2°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 2.24E-11mmHg at 25°C
• CAS DataBase Reference: TILORONE ANALOG R11-877DA(CAS DataBase Reference)
• NIST Chemistry Reference: TILORONE ANALOG R11-877DA(35556-06-0)
• EPA Substance Registry System: TILORONE ANALOG R11-877DA(35556-06-0)

Safety Data

• Hazardous Substances Data: 35556-06-0(Hazardous Substances Data)

Usage

Definition

Different sources of media describe the Definition of 35556-06-0 differently. You can refer to the following data:
1. A crystalline hydrated compound that contains three molecules of water of crystallization per molecule of compound.
2. trihydrate: A crystalline hydratethat contains three moles of waterper mole of compound.

InChI:InChI=1/C20H22N2O2S.2ClH/c1-21(2)11-17(23)13-5-7-19-15(9-13)16-10-14(6-8-20(16)25-19)18(24)12-22(3)4;;/h5-10H,11-12H2,1-4H3;2*1H

Upstream product

• 35556-07-1 2,8-bis(bromoacetyl)dibenzothiophene 

Relevant articles and documents

Bis basic substituted polycyclic aromatic compounds. A new class of antiviral agents. 8. Bis basic derivatives of carbazole, dibenzofuran, and dibenzothiophene

A series of bisalkamine esters, bis-basic ethers, and bis-basic ketones of carbazole, N-ethylcarbazole, dibenzofuran, and dibenzothiophene was synthesized and evaluated for antiviral activity. The series also induced two bis-basic alkanes of N-ethylcarbazole and one bis-basic carboxamide of dibenzofuran. Structure-activity relationships indicated that within the carbazole and N-ethylcarbazole series the bisalkamine esters gave the most active derivatives while the bis-basic ketone derivatives of dibenzofuran and dibenzothiophene afforded the more potent compounds within the respective series. The [6,5,6] heterocyclic nuclei were compared with [6,5,6] aromatic nuclei (fluorene and fluoren-9-one) including tilorone with respect to antiviral activity against encephalomyocarditis (EMC) virus. Maximum activity was associated with the bis-basic ketone side chain and fluoren-9-one nucleus.