35559-18-3Relevant articles and documents
Structure activity relationships, multidrug resistance reversal and selectivity of heteroarylphenyl ABCG2 inhibitors
K?hler, Sebastian C.,Vahdati, Sahel,Scholz, Matthias S.,Wiese, Michael
, p. 483 - 500 (2018/02/14)
An overexpression of the transmembrane ATP-binding cassette transporter G2 (ABCG2, BCRP) in cancer tissues is supposed to play a role in the multidrug resistance (MDR) of tumors resulting in an inefficient chemotherapy. Therefore, co-administration of sel