35559-38-7Relevant academic research and scientific papers
Organocatalytic asymmetric synthesis of sulfoxides from sulfenic acid anions mediated by a cinchona -derived phase-transfer reagent
Gelat, Fabien,Jayashankaran, Jayadevan,Lohier, Jean-Francois,Gaumont, Annie-Claude,Perrio, Stephane
supporting information; experimental part, p. 3170 - 3173 (2011/08/06)
Preliminary results concerning a conceptually novel route to chiral sulfoxides based on the asymmetric alkylation of sulfenate salts with alkyl halides mediated by a chiral phase-transfer catalyst are described. As a representative example, o-anisyl methyl sulfoxide was produced in 96% yield and with an enantiomeric excess of 58% using commercial cinchonidinium derivative 2a.
