35572-11-3Relevant academic research and scientific papers
5-MEMBERED HETEROCYCLIC COMPOUND
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Page/Page column 79, (2010/07/03)
Provided is a compound having a superior acid secretion suppressive action, which shows an antiulcer activity and the like. A compound represented by the formula (I) or a salt thereof: wherein ring A is a saturated or unsaturated 5-membered heterocycle co
Selective fluorodesulfurization of benzo- and pyrido-oxazine derivatives
Yin, Bin,Inagi, Shinsuke,Fuchigami, Toshio
scheme or table, p. 2146 - 2150 (2010/11/02)
Selective fluorodesulfurization of 3-aryl-2-phenylthio-2H-benzo[b][1,4] oxazine derivatives was successfully carried out using various N-halogenosuccinimides as oxidizing reagent in the presence of Et 3N3HF to provide the corresponding monofluo
ACID SECRETION INHIBITOR
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Page/Page column 57, (2009/01/24)
The present invention provides a compound having a superior acid secretion inhibitory action, an antiulcer activity and the like. A proton pump inhibitor containing a compound represented by the formula (I) wherein ring A is a saturated or unsaturated 5- or 6-membered ring group optionally having, as a ring-constituting atom besides carbon atom, 1 to 4 hetero atoms selected from a nitrogen atom, an oxygen atom and a sulfur atom, ring-constituting atoms X1 and X2 are each a carbon atom or a nitrogen atom, a ring-constituting atom X3 is a carbon atom, a nitrogen atom, an oxygen atom or a sulfur atom, R1 is an optionally substituted aryl group or an optionally substituted heteroaryl group, R2 is an optionally substituted alkyl group, an optionally substituted aryl group or an optionally substituted heteroaryl group, R3 is an aminomethyl group optionally substituted by 1 or 2 lower alkyl groups, which is a substituent on a ring-constituting atom other than X1, X2 and X3, and ring A optionally further has substituent(s) selected from a lower alkyl group, a halogen atom, a cyano group and an oxo group, or a salt thereof or a prodrug thereof.
