35576-47-7

Upstream product

• 37014-08-7 3-methoxyphenylthiourea 
• 74-88-4 methyl iodide 
• 536-90-3 m-Anisidine 
• 21258-09-3 N-benzoyl-N′-(3-methoxyphenyl)thiourea 

Downstream Products

• 89069-27-2 3-(3-methoxyphenyl)-2-methylthio-4(3H)-pyrimidinone 
• 89069-50-1 3-(3-methoxyphenyl)-2-methylthio-6-phenyl-4(3H)-pyrimidinones 
• 88352-31-2 2-S-Methyl-1-(3-methoxyphenyl)-5-(2-furfuryl)isodithiobiuret 
• 88352-18-5 2-S-Methyl-1-(3-methoxyphenyl)-5-(2-pyridyl)isodithiobiuret 
• 82635-92-5 2-[3-(3-Methoxy-phenyl)-2-methyl-isothioureidomethylene]-malonic acid diethyl ester 
• 82636-19-9 1-(3-Methoxy-phenyl)-2-methylsulfanyl-6-oxo-1,6-dihydro-pyrimidine-5-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

Synthesis and Biological Activity of Some New 1-Aryl-2-S-methyl-5-(2-pyridyl/2-furfuryl)isodithiobiurets

A number of 1-aryl-2-S-methyl-5-(2-pyridyl/2-furfuryl)isodithiobiurets (II and III) have been synthesized by the condensation of various N-aryl-S-methylisothioureas (V) with 2-pyridyl- and 2-furfurylisothiocyanates and tested for anthelmintic, antiamoebic, antitrichomonal, antileishmanial and antimicrobial activities.

Synthesis & Pharmacological Evaluation of Ethyl 3-Substituted-phenyl-2-methylmercapto/ phenyl/ methyl-4(3H)-pyrimidone-5-carboxylates

A number of ethyl 3-substituted-phenyl-2-methylmercapto/ phenyl/ methyl-4(3H)-pyrimidone-5-carboxylates (V) have been prepared by the reaction of amidines (III) with diethyl ethoxymethylenemalonate.In order to confirm the structure (V), ethyl 3-(2'-methylphenyl)-2-methylmercapto-4(3H)pyrimidone-5-carboxylate (103) has been transformed into the earlier synthesised 3-(2'-methylphenyl)-2-methylmercapto-4(3H)-pyrimidone (115) by decarboxylation of 3-(2'-methylphenyl)-2-methylmercapto-4(3H)-pyrimidone-5-carboxylic acid (114), obtained by the alkaline hydrolysis of 103.Someof these compounds have shown antiinflammatory, diuretic and antipassive cutaneous anaphylaxis activities.